LAG3 Antikörper (N-Term) (Atto 647N)

Produktnummer ABIN1169111

Der Maus Monoklonal anti-LAG3 Antikörper wird verwendet zum Nachweis von LAG3 in Proben von Human. Er wurde validiert für ICC und FACS.

Kurzübersicht für LAG3 Antikörper (N-Term) (Atto 647N) (ABIN1169111)

Target: LAG3 (Lymphocyte-Activation Gene 3 (LAG3))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser LAG3 Antikörper ist konjugiert mit Atto 647N

Applikation: Immunocytochemistry (ICC), Flow Cytometry (FACS)

Klon: 17B4

Produktdetails anti-LAG3 Antikörper (Atto 647N)

Bindungsspezifität: N-Term

Verwendungszweck: anti-LAG-3 (human), mAb (17B4) (ATTO 647N)

Spezifität: Recognizes human LAG-3.

Produktmerkmale: Monoclonal Antibody. Recognizes human LAG-3. Isotype: Mouse IgG1. Clone: 17B4. Applications: FACS, ICC. Liquid. In PBS containing 0.02 % sodium azide. Lymphocyte activation gene 3 (LAG-3, CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4.

Reinheit: >95 % (SDS-PAGE)

Immunogen: Synthetic peptide corresponding to 30 aa in the N-terminus of human LAG-3.

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

New ATTO-fluorescent antibodies show increased photostability, outstanding brightness and intense signals. ATTO dyes are thermally stable, resistant to environmental changes and show no significant isomerization. ATTO 647N shows red fluorescence (lambdaabs (max): 645nm, lambdaem (max): 669nm, epsilonmax: 120'000).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: In PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Do not freeze.Protect from light.

Lagerung: 4 °C

Informationen zur Lagerung:

+4°C

+4°C

Keep conjugated formats at +4°C. Stable for at least 1 year after receipt when stored at +4°C.

Haltbarkeit: 12 months

Details zu LAG3

Target: LAG3 (Lymphocyte-Activation Gene 3 (LAG3))

Andere Bezeichnung: LAG-3

Hintergrund:

Alternate Names/Synonyms: Lymphocyte Activation Gene-3, FDC Protein, CD223

Product Description: Lymphocyte activation gene 3 (LAG-3, CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4.

UniProt: P18627

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints