LAG3 Antikörper (N-Term) (Atto 488)

Produktnummer ABIN1169108

Der Maus Monoklonal Anti-LAG3-Antikörper wurde für ICC und FACS validiert. Er ist geeignet, LAG3 in Proben von Human zu detektieren.

Kurzübersicht für LAG3 Antikörper (N-Term) (Atto 488) (ABIN1169108)

Target: LAG3 (Lymphocyte-Activation Gene 3 (LAG3))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser LAG3 Antikörper ist konjugiert mit Atto 488

Applikation: Immunocytochemistry (ICC), Flow Cytometry (FACS)

Klon: 17B4

Produktdetails anti-LAG3 Antikörper (Atto 488)

Bindungsspezifität: N-Term

Spezifität: Recognizes human LAG-3.

Kreuzreaktivität: Human

Reinheit: >95 % (SDS-PAGE)

Immunogen: Synthetic peptide corresponding to 30 aa in the N-terminus of human LAG-3.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

New ATTO-fluorescent antibodies show increased photostability, outstanding brightness and intense signals. ATTO dyes are thermally stable, resistant to environmental changes and show no significant isomerization. ATTO 488 shows bright green fluorescence (lambdaabs (max): 501nm, lambdaem (max): 523nm, epsilonmax: 90'000).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: In PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Short Term Storage: +4°C
Long Term Storage: +4°C
Keep conjugated formats at +4°C. Stable for at least 1 year after receipt when stored at +4°C.

Haltbarkeit: 12 months

Details zu LAG3

Target: LAG3 (Lymphocyte-Activation Gene 3 (LAG3))

Andere Bezeichnung: LAG-3

Hintergrund: Lymphocyte activation gene 3 (LAG-3, CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4.

UniProt: P18627

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints