SIRT2 Antikörper

Produktnummer ABIN1169092

Dieser Maus Monoklonal Antikörper detektiert spezifisch SIRT2 in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für SIRT2 Antikörper (ABIN1169092)

Target: SIRT2 (Sirtuin 2 (SIRT2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SIRT2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Klon: S2R233-1

Produktdetails anti-SIRT2 Antikörper

Verwendungszweck: anti-Sirtuin 2 (human), mAb (S2R233-1)

Spezifität: Recognizes human sirtuin 2. Detects a band of ~45 kDa by Western blot.

Produktmerkmale: Monoclonal Antibody. Recognizes human sirtuin 2. Detects a band of ~45 kDa by Western blot. Isotype: Mouse IgG2bkappa. Clone: S2R233-1. Applications: ELISA, WB. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. Sirtuin-2 is a NAD-dependent protein deacetylase, which deacetylates the 'Lys-40' of a-tubulin. It is involved in the control of mitotic exit in the cell cycle. Furthermore, a variety of age-associated diseases such as type 2 diabetes, obesity, osteoporosis, and Alzheimer's disease are associated with sirtuins. Selective inhibition of Sirtuin-2 achieves neuroprotection and identifies Sirtuin-2 to be a potential therapeutic avenue in Huntington's and Parkinson's disease.

Sterilität: 0.2 μm filtered

Immunogen: Recombinant human sirtuin 2.

Isotyp: IgG2b kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 0.2μm-filtered solution in PBS, pH 7.4.

Konservierungsmittel: Without preservative

Handhabung: After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung:

+4°C

-20°C

Stable for at least 1 year after receipt when stored at -20°C.

Haltbarkeit: 12 months

Details zu SIRT2

Target: SIRT2 (Sirtuin 2 (SIRT2))

Andere Bezeichnung: Sirtuin 2

Hintergrund:

Alternate Names/Synonyms: SIRT2, NAD-dependent Deacetylase Sirtuin-2, SIR2-like protein 2, SIR2L2

Product Description: Sirtuin-2 is a NAD-dependent protein deacetylase, which deacetylates the 'Lys-40' of a-tubulin. It is involved in the control of mitotic exit in the cell cycle. Furthermore, a variety of age-associated diseases such as type 2 diabetes, obesity, osteoporosis, and Alzheimer's disease are associated with sirtuins. Selective inhibition of Sirtuin-2 achieves neuroprotection and identifies Sirtuin-2 to be a potential therapeutic avenue in Huntington's and Parkinson's disease.

UniProt: Q8IXJ6