Clusterin Antikörper
Kurzübersicht für Clusterin Antikörper (ABIN1169057)
Target
Alle Clusterin (CLU) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Spezifität
- Recognizes mouse clusterin. Detects a band of ~48 kDa by Western blot.
-
Kreuzreaktivität
- Maus
-
Sterilität
- 0.2 μm filtered
-
Immunogen
- Recombinant mouse nuclear clusterin.
-
-
anti-Clusterin (CLU) (AA 229-446) antibody
CLU Reaktivität: Schwein WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Clusterin (CLU) (AA 331-449) antibodyCLU Reaktivität: Human, Ratte, Maus ELISA, IHC (p), FACS, IHC (fro), IF (cc), IF (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Clusterin (CLU) (AA 227-448) antibodyCLU Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Clusterin (CLU) (AA 228-449) antibodyCLU Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Clusterin (CLU) (AA 226-447) antibodyCLU Reaktivität: Kaninchen WB, IHC, IP, ICC Wirt: Maus Monoclonal C10 unconjugated
anti-Clusterin (CLU) (AA 71-99), (N-Term) antibodyCLU Reaktivität: Human, Ratte, Maus WB, IHC (p), FACS Wirt: Kaninchen Polyclonal RB18701 unconjugated
anti-Clusterin (CLU) (AA 23-120) antibodyCLU Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Clusterin (CLU) (C-Term) antibodyVerified CLU Reaktivität: Human WB, IHC, ELISA, IF Wirt: Ziege Polyclonal unconjugated
anti-Clusterin (CLU) (AA 227-447) antibodyCLU Reaktivität: Ratte WB, IHC Wirt: Maus Monoclonal C1 unconjugated
anti-Clusterin (CLU) (C-Term) antibodyVerified CLU Reaktivität: Ratte, Maus WB, ELISA, IF Wirt: Ziege Polyclonal unconjugated
-
-
Applikationshinweise
- Optimal working dilution should be determined by the investigator.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- Lot specific
-
Buffer
- 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
-
Konservierungsmittel
- Without preservative
-
Lagerung
- 4 °C,-20 °C
-
Informationen zur Lagerung
-
Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. -
Haltbarkeit
- 6 months
-
-
- Clusterin (CLU)
-
Andere Bezeichnung
- Clusterin
-
Hintergrund
- Clusterin shares homology with the small heat shock protein family of molecular chaperones. The mature secreted form of the protein is a glycosylated, 80- kDa disulfide-linked heterodimer of alpha and beta subunits (produced by internal cleavage). Clusterin is expressed in virtually all tissues and found in all fluids. It is involved in numerous physiological processes important for carcinogenesis and tumor growth, including apoptotic cell death, cell cycle regulation, DNA repair, cell adhesion, tissue remodeling, lipid transportation, membrane recycling, and immune system regulation. Clusterin also exists as a nuclear protein. The secreted form of Clusterin has extracellular chaperone and anti-apoptotic activities while the nuclear form acts as a proapoptotic factor.
-
UniProt
- Q06890
-
Pathways
- Apoptose, Negative Regulation of intrinsic apoptotic Signaling
Target
-
