CXCL12 Antikörper
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- Target Alle CXCL12 Antikörper anzeigen
- CXCL12 (Chemokine (C-X-C Motif) Ligand 12 (CXCL12))
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Reaktivität
- Human
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Wirt
- Ziege
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Klonalität
- Polyklonal
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Konjugat
- Dieser CXCL12 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA), Functional Studies (Func)
- Spezifität
- Reacts with Stromal Cell Derived Factor-1 beta (SDF-1 beta).
- Kreuzreaktivität (Details)
- Species reactivity (tested):Human.
- Aufreinigung
- Affinity Chromatography.
- Immunogen
- E. Coli derived Recombinant recombinant Human SDF-1 beta
- Isotyp
- IgG
- Top Product
- Discover our top product CXCL12 Primärantikörper
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- Applikationshinweise
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Indirect ELISA: To detect Human SDF-1 beta by Indirect ELISA (using 100 μL/well antibodysolution) a concentration of at least 0.5 μg/mL of this antibody is required. This antigenaffinity purified antibody, in conjunction with compatible secondary reagents, allows thedetection of 0.2-0.4 ng/well of recombinant Human SDF-1 beta. Sandwich ELISA: To detect Human SDF-1 beta by Sandwich ELISA (using 100 μL/wellantibody solution) a concentration of 0.5-2.0 μg/mL of this antibody is required. Thisantigen affinity purified antibody, in conjunction with Biotinylated Anti-Human SDF-1 beta(PP1068B1 or PP1068B2) as a detection antibody, allows the detection of at least 0.2-0.4 ng/well of recombinant Human SDF-1 beta. Western Blot: To detect Human SDF-1 beta by Western Blot analysis this antibody can beused at a concentration of 0.1-0.2 μg/mL. Used in conjunction with compatible secondaryreagents the detection limit for recombinant hSDF-1 bet is 1.5-3.0 ng/lane, under eitherreducing or non-reducing conditions.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Rekonstitution
- Centrifuge vial prior to opening! Restore in sterile water to a concentration of 0.1-1.0 mg/mL.
- Buffer
- PBS, pH 7.2 without preservatives.
- Konservierungsmittel
- Without preservative
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.
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- Target
- CXCL12 (Chemokine (C-X-C Motif) Ligand 12 (CXCL12))
- Andere Bezeichnung
- CXCL12 / SDF1 (CXCL12 Produkte)
- Synonyme
- IRH antikoerper, PBSF antikoerper, SCYB12 antikoerper, SDF1 antikoerper, TLSF antikoerper, TPAR1 antikoerper, CINC-1 antikoerper, Gro1 antikoerper, Pbsf antikoerper, Scyb12 antikoerper, Sdf1 antikoerper, Tlsf antikoerper, Tpar1 antikoerper, Fsp antikoerper, KC antikoerper, Mgsa antikoerper, N51 antikoerper, Scyb1 antikoerper, gro antikoerper, sdf-1 antikoerper, sdf1 antikoerper, xSDF-1 antikoerper, SDF-1 antikoerper, cxcl12 antikoerper, sdf-1a antikoerper, sdf1a antikoerper, wu:fa55e10 antikoerper, wu:fc16h12 antikoerper, wu:fj84c02 antikoerper, C-X-C motif chemokine ligand 12 antikoerper, C-X-C motif chemokine ligand 1 antikoerper, chemokine (C-X-C motif) ligand 12 antikoerper, chemokine (C-X-C motif) ligand 1 antikoerper, C-X-C motif chemokine ligand 12 L homeolog antikoerper, chemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1) antikoerper, CXCL12 antikoerper, cxcl12 antikoerper, Cxcl1 antikoerper, Cxcl12 antikoerper, cxcl12.L antikoerper, cxcl12a antikoerper
- Hintergrund
- SDF1 alpha and 1 beta are small cytokines that belong to the intercrine family, members of which activate leukocytes and are often induced by proinflammatory stimuli such as lipopolysaccharide, TNF or IL1. SDF1 alpha has been shown to be chemotactic for lymphocytes and is recently reported to be a ligand for CXCR4 (LESTR/fusin), a co-receptor for HIV1 entry into T cells. SDF-1 binding to CXCR4 inhibits HIV1 entry.Synonyms: C-X-C motif chemokine 12, IRH, Intercrine reduced in hepatomas, PBSF, Pre-B cell growth-stimulating factor, SDF1A, SDF1B, Stromal cell-derived factor 1, hIRH
- Molekulargewicht
- approx. 150 kDa
- Gen-ID
- 6387
- NCBI Accession
- NP_000600
- UniProt
- P48061
- Pathways
- Regulation of Cell Size, CXCR4-mediated Signaling Events, Negative Regulation of intrinsic apoptotic Signaling
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