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CCL8 Antikörper

CCL8 Reaktivität: Human WB, EIA, Func Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN116143
  • Target Alle CCL8 Antikörper anzeigen
    CCL8 (Chemokine (C-C Motif) Ligand 8 (CCL8))
    Reaktivität
    • 42
    • 11
    • 2
    • 2
    • 2
    Human
    Wirt
    • 44
    • 11
    • 1
    • 1
    Kaninchen
    Klonalität
    • 45
    • 12
    Polyklonal
    Konjugat
    • 31
    • 9
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CCL8 Antikörper ist unkonjugiert
    Applikation
    • 31
    • 24
    • 14
    • 14
    • 12
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA), Functional Studies (Func)
    Spezifität
    Human Macrophage Chemotactic Protein-2 (MCP-2).
    Aufreinigung
    Affinity chromatography.
    Immunogen
    Highly pure (>98%) recombinant hMCP-2.
    Top Product
    Discover our top product CCL8 Primärantikörper
  • Applikationshinweise
    Neutralization: To yield one-half maximal inhibition [ND50] of the biological activity ofhMCP-2 (100.00 ng/mL), a concentration of 12-16 μg/mL of this antibody is required. ELISA: To detect hMCP-2 by Indirect ELISA (using 100 l/well antibody solution) aconcentration of at least 0.5-0.2 μg/mL of this antibody is required. This antigen affinitypurified antibody, in conjunction with compatible secondary reagents, allows the detectionof 0.2-0.4 ng/well of recombinant hMCP-2. Sandwich: To detect hMCP-2 by sandwich ELISA (using 100 μL/well antibody solution) aconcentration of 0.5-2.0 μg/mL of this antibody is required. This antigen affinity purifiedantibody, in conjunction with Biotinylated Anti-Human MCP-2 (PP1045B1/B2) as adetection antibody, allows the detection of at least 0.2 - 0.4 ng/well of recombinanthMCP-2. Western Blot: To detect hMCP-2 by Western Blot analysis this antibody can be used at aconcentration of 0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagentsthe detection limit for recombinant hMCP-2 is 1.5-3.0 ng/lane, under either reducing ornon-reducing conditions.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Rekonstitution
    Restore in sterile water to a concentration of 0.1-1.0 mg/mL.
    Buffer
    PBS, pH 7.2 without preservatives.
    Konservierungsmittel
    Without preservative
    Handhabung
    Centrifuge vial prior to opening!
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store the antibody in the dark at 2-8 °C. Do Not Freeze! Avoid prolonged exposure to light.
  • Target
    CCL8 (Chemokine (C-C Motif) Ligand 8 (CCL8))
    Andere Bezeichnung
    MCP2 / CCL8 (CCL8 Produkte)
    Synonyme
    HC14 antikoerper, MCP-2 antikoerper, MCP2 antikoerper, SCYA10 antikoerper, SCYA8 antikoerper, 1810063B20Rik antikoerper, AB023418 antikoerper, Mcp2 antikoerper, Scya8 antikoerper, C-C motif chemokine ligand 8 antikoerper, chemokine (C-C motif) ligand 8 antikoerper, C-C motif chemokine 8 antikoerper, monocyte chemoattractant protein-2 precursor antikoerper, CCL8 antikoerper, Ccl8 antikoerper, LOC101119572 antikoerper, MCP-2 antikoerper
    Hintergrund
    MCP 2 (Monocyte Chemoattractant Protein 2) is a chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils. MCP 2 is important to inflammatory host responses, and is found in the highest concentration in the small intestine and peripheral blood cells. This protein is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. By recruiting leukocytes to sites of inflammation this cytokine may contribute to tumor-associated leukocyte infiltration and to the antiviral state against HIV infection.Synonyms: C-C motif chemokine 8, CCL-8, HC14, MCP-2, Monocyte Chemotactic Protein-2, Monocyte chemoattractant protein 2, SCYA10, SCYA8, Small-inducible cytokine A8
    Gen-ID
    6355
    NCBI Accession
    NP_005614
    UniProt
    P80075
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