CCL8 Antikörper (AA 24-97)

Produktnummer ABIN6719605

Produktdetails anti-CCL8 Antikörper

Target: CCL8 (Chemokine (C-C Motif) Ligand 8 (CCL8))

Bindungsspezifität: AA 24-97

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCL8 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for CCL8 detection. Tested with IHC-P, ELISA(Cap) in Mouse,Rat.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for CCL8 detection. Tested with IHC-P, ELISA(Cap) in Mouse,Rat.

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived mouse CCL8 recombinant protein (Position: G24-P97).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Application details: Immunohistochemistry(Paraffin-embedded Section)|0.5-1 μg/mL ELISA(Cap)|1-5 μg/mL

Kommentare:

Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu CCL8

Target: CCL8 (Chemokine (C-C Motif) Ligand 8 (CCL8))

Andere Bezeichnung: Ccl8 (CCL8 Produkte)

Synonyme: HC14 antikoerper, MCP-2 antikoerper, MCP2 antikoerper, SCYA10 antikoerper, SCYA8 antikoerper, 1810063B20Rik antikoerper, AB023418 antikoerper, Mcp2 antikoerper, Scya8 antikoerper, C-C motif chemokine ligand 8 antikoerper, chemokine (C-C motif) ligand 8 antikoerper, C-C motif chemokine 8 antikoerper, monocyte chemoattractant protein-2 precursor antikoerper, CCL8 antikoerper, Ccl8 antikoerper, LOC101119572 antikoerper, MCP-2 antikoerper

Hintergrund:

Synonyms: C-C motif chemokine 8, Monocyte chemoattractant protein 2, Monocyte chemotactic protein 2, MCP-2, Small-inducible cytokine A8, Ccl8, Mcp2, Scya8

Background: CCL8, also known as monocyte chemoattractant protein 2 (MCP2), is a protein that in humans is encoded by the CCL8 gene. It is a small cytokine belonging to the CC chemokine family. The CCL8 protein is produced as a precursor containing 109 amino acids, which is cleaved to produce mature CCL8 containing 75 amino acids. The gene for CCL8 is encoded by 3 exons and is located within a large cluster of CC chemokines on chromosome 17q11.2 in humans. MCP-2 is chemotactic for and activates many different immune cells, including mast cells, eosinophils and basophils, (that are implicated in allergic responses), and monocytes, T cells, and NK cells that are involved in the inflammatory response. CCL8 elicits its effects by binding to several different cell surface receptors called chemokine receptors. These receptors include CCR1, CCR2B, CCR3 and CCR5.

Gen-ID: 20307

UniProt: Q9Z121