IL-11 Antikörper (Biotin)

Produktnummer ABIN116101

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch IL-11 in WB und EIA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für IL-11 Antikörper (Biotin) (ABIN116101)

Target: IL-11 (IL11) (Interleukin 11 (IL11))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL-11 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-IL-11 Antikörper (Biotin)

Spezifität: Human Interleukin-11.

Aufreinigung: Affinity chromatography.

Immunogen: Highly pure (>98%) recombinant hIL-11 (human IL-11).

Anwendungsinformationen

Applikationshinweise: ELISA: To detect hIL-11 by direct ELISA (using 100 l/well antibody solution) this antibody can beused at a concentration of 0.15 - 0.30 μg/mL. Used in conjunction with compatiblesecondary reagents, allows the detection of at least 0.2 ng/well of recombinant hIL-11. Western Blot: To detect hIL-11 by Western Blot analysis this antibody can be used at a concentration of0.1 - 0.2 μg/mL. Used in conjunction with compatible secondary reagents the detectionlimit for recombinant hIL-11 is 1.5 - 3.0 ng/lane, under either reducing or non-reducingconditions.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore in sterile PBS containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL.

Buffer: PBS, pH 7.2 without preservatives.

Konservierungsmittel: Without preservative

Handhabung: Avoid repeated freezing and thawing. Centrifuge vial prior to opening!

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 4-8 °C for one month or at -20 °C for longer.

Details zu IL-11

Target: IL-11 (IL11) (Interleukin 11 (IL11))

Andere Bezeichnung: Interleukin-11 / IL11

Hintergrund: Interleukin 11 is a pleiotropic cytokine produced by mesenchymal-derived adherent cells. IL11 shares many functions of IL6 and LIF, including potentiation of megakaryocyte activity, enhancement of human myeloma cell proliferation, and enhancement of hepatic acute phase protein production. Interleukin 11 directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells, and induces megakaryocyte maturation resulting in increased platelet production. Clinically it is used to prevent severe thrombocytopenia and the reduction of the need for platelet transfusion following myelosuppressive chemotherapy.Synonyms: AGIF, Adipogenesis inhibitory factor, IL-11

Gen-ID: 3589

NCBI Accession: NP_000632

UniProt: P20809

Pathways: JAK-STAT Signalweg, Negative Regulation of Hormone Secretion