FGF2 Antikörper

Produktnummer ABIN115776

Der Maus Monoklonal anti-FGF2 Antikörper (ABIN115776) detektiert spezifisch FGF2 in WB und EIA. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für FGF2 Antikörper (ABIN115776)

Target: FGF2 (Fibroblast Growth Factor 2 (Basic) (FGF2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser FGF2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-FGF2 Antikörper

Spezifität: Human Fibroblast Growth Factor basic (FGF-basic).

Aufreinigung: Protein A chromatography.

Immunogen: Recombinant hFGF-basic

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: In a sandwich ELISA (assuming 100 ?l/well), a concentration of 2 μg/mL of thisantibody will detect at least 0.2 ng/well of recombinant human FGF-basic when used withbiotinylated antigen affinity purified anti-human FGF-basic as the detection antibody at aconcentration of 1 μg/mL. Western Blot: To detect hFGF-basic by Western Blot analysis this antibody can be used at aconcentration of 0.25-0.50 μg/mL. Used in conjunction with compatible secondary reagentsthe detection limit for recombinant hFGF-basic is 1.0-2.0 ng/lane, under non-reducingconditions.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore in sterile water to a concentration of 1.0 mg/mL.

Buffer: PBS without preservatives.

Konservierungsmittel: Without preservative

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody at 2-8 °C. DO NOT FREEZE! Avoid prolonged exposure to light.

Details zu FGF2

Target: FGF2 (Fibroblast Growth Factor 2 (Basic) (FGF2))

Andere Bezeichnung: FGF Basic / FGF2

Hintergrund: FGF basic (FGF2) is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. FGF2 is involved in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. FGF2 mRNA contains multiple polyadenylation sites, and is alternatively translated from AUG and non-AUG (CUG) initiation codons resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.Synonyms: BFGF, FGFB, Fibroblast growth factor 2 (basic), HBGF-2, HBGF2, Heparin-binding growth factor 2

Gen-ID: 2247

NCBI Accession: NP_001997

UniProt: P09038

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, C21-Steroid Hormone Metabolic Process, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Protein targeting to Nucleus, S100 Proteine