This antibody reacts to ventricular myosin light chain.
Aufreinigung
Immunoaffinity chromatography
Immunogen
Recombinant human myosin (cardiac) light chain fragment. Remarks: The antibody was raised in rabbits by immunization with the recombinant Human Myosin (Cardiac) Light Chain fragment. The amino acid sequence of the recombinant Human Myosin (Cardiac) Light Chain fragment is 100% homologous to the amino acid sequence of the human serum Myosin (Cardiac) Light Chain fragment.
MYL3
Reaktivität: Human
WB
Wirt: Maus
Polyclonal
unconjugated
Applikationshinweise
ELISA. Western Blot. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Rekonstitution
Restore with 0.05 mL of deionized water
Konzentration
1.0 mg/mL
Buffer
0.05 M phosphate buffer, 0.1 M NaCl, pH 7.2. AZIDE FREE
Konservierungsmittel
Azide free
Handhabung
Avoid repeated freezing and thawing.
Lagerung
-20 °C
Informationen zur Lagerung
Prior to reconstitution store at -70 °C. Following reconstitution store the antibody (in aliquots) at -20 °C for 6 months.
Haltbarkeit
6 months
Target
MYL3/CMLC1 (MYL3)
(Myosin, Light Chain 3 (MYL3))
Andere Bezeichnung
MYL3
Hintergrund
Human ventricular myosin light chain (MLC-I, Essential Myosin Light Chain Isoform) is a 21 kDa cardiac contractile protein, which is one of component of myosin structure. The protein MLC-I is present in the contractile apparatus and not in cytosol. In severe congestive heart failure (CHF), myofibrils may degenerate and, subsequently, the myofibrillar components may be released into the circulation. The increased blood levels of MLC-I could indicate morphological changes in CHF, myocardial infarction, structural abnormalities in viable myocytes also observed in non-ischaemic CHF, myocardial necrosis.Synonyms: CMLC1, Cardiac myosin light chain 1, MLC1SB, Myosin light chain 1, Myosin light chain 3, Ventricular/slow twitch myosin alkali light chain, slow-twitch muscle B/ventricular isoform