Thrombospondin 1 Antikörper (THBS1)

Details for Product anti-THBS1 Antibody No. ABIN115006, Anbieter: Anmelden zum Anzeigen
Antigen
  • THBS
  • THBS-1
  • TSP
  • TSP-1
  • TSP1
  • Thbs-1
  • tbsp1
  • thrombospondin-1
  • thbs
  • thbs-1
  • tsp
  • tsp-1
  • tsp1
  • Tsp1
  • THBS1
  • Tsp-1
  • wu:fc48c03
  • si:dkey-11e23.1
  • tsp2
  • thrombospondin 1
  • thrombospondin 1 S homeolog
  • thrombospondin 1b
  • thrombospondin 2 L homeolog
  • THBS1
  • Thbs1
  • thbs1.S
  • thbs1b
  • thbs1
  • thbs2.L
Reaktivität
Säugetier
158
63
57
25
18
18
16
16
3
3
1
1
1
Wirt
Maus
127
48
32
Klonalität (Klon)
Monoklonal ()
Konjugat
Dieser Thrombospondin 1 Antikörper ist unkonjugiert
28
16
9
4
4
3
1
Applikation
Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
167
113
56
37
32
24
17
17
10
8
4
4
3
3
2
2
2
2
2
2
2
2
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen BALB/C mice were injected with reduced and alkylated purified human TSP (fully denatured) from the supernatant of thrombin-activated platelets.
Klon A6-1
Isotyp IgG1
Spezifität This antibody is specific to 450 kDa protein (non-reduced) and 170 to 180 kDa (reduced) form of Thrombospondin.
Cellular Localization: Secretory granules, Golgi complex, endoplasmic reticulum
Reinigung Purified
Andere Bezeichnung Thrombospondin-1 (THBS1) (THBS1 Antibody Abstract)
Hintergrund Thrombospondin is a protein from platelet a granules. It is secreted at sites of platelet activation and aggregation and is involved in the differentiation of leukocytes, fibroblasts, smooth muscle and endothelial cells.Synonyms: TSP, TSP1
Gen-ID 7057
NCBI Accession NP_003237
UniProt P07996
Pathways Autophagie
Applikationshinweise Immunofluorescence. Immunoprecipitation. Western Blot. Immunohistochemistry on paraffin embedded sections: diluted of 1: 25-1: 50 in an ABC method (30 minutes at room temperature). Formalin fixedparaffin embedded tissue sections require high temperature antigen unmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining. Recommended Positive Control: Tonsil
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Buffer Sodium azide as preservative
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Bilder des Herstellers
Immunohistochemistry (IHC) image for anti-Thrombospondin 1 (THBS1) antibody (ABIN115006) Formalin fixed paraffin embedded human tonsil stained with Thrombospondin antibody. A...
Allgemeine Veröffentlichungen Galvin, Vance, Dixit, Fink, Frazier: "Interaction of human thrombospondin with types I-V collagen: direct binding and electron microscopy." in: The Journal of cell biology, Vol. 104, Issue 5, pp. 1413-22, 1987 (PubMed).

Dixit, Galvin, ORourke, Frazier: "Monoclonal antibodies that recognize calcium-dependent structures of human thrombospondin. Characterization and mapping of their epitopes." in: The Journal of biological chemistry, Vol. 261, Issue 4, pp. 1962-8, 1986 (PubMed).

Dixit, Haverstick, ORourke, Hennessy, Grant, Santoro, Frazier: "Effects of anti-thrombospondin monoclonal antibodies on the agglutination of erythrocytes and fixed, activated platelets by purified thrombospondin." in: Biochemistry, Vol. 24, Issue 16, pp. 4270-5, 1985 (PubMed).

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