CCL2 Antikörper (Biotin)

Produktnummer ABIN114714

Der Biotin-konjugierte Maus Monoklonal anti-CCL2 Antikörper (Klon S101) (ABIN114714) detektiert spezifisch CCL2 in EIA. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für CCL2 Antikörper (Biotin) (ABIN114714)

Target: CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CCL2 Antikörper ist konjugiert mit Biotin

Applikation: Enzyme Immunoassay (EIA)

Klon: S101

Produktdetails anti-CCL2 Antikörper (Biotin)

Aufreinigung: Protein G affinity purified

Immunogen: Purified recombinant human MCP-1

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: This Biotin-conjugated monoclonal antibody can be used as a tracer/detectionantibody in sandwich ELISA applications for human MCP-1 detection in combination with acapture antibody. Suggested Capture Coating Dose: approx. 0.3g/mL, Substrate: TMB. If theabove suggested conditions are followed approximately 1.5 pg/mL of MCP-1 inserum/plasma or 4 pg/mL of MCP-1 in medium can be detected with an assay range of0-1600 pg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.01 M PBS, pH 7.0±0.1, 0.1 % Proclin-300, 1 % Gelatin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Details zu CCL2

Target: CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))

Andere Bezeichnung: MCP1 / CCL2

Hintergrund: Monocyte chemotactic and activating factor (MCAF) is also called monocyte chemotactic protein-1 (MCP-1) and chemokine (C-C motif) ligand 2 (CCL2). It is primarily secreted by monocytes, macrophages and dendritic cells. This cytokine displays chemotactic activity for monocytes, T-cells, and basophils, but not for neutrophils or eosinophils. MCAF causes the degranulation of basophils and mast cells, and augments the activity of monocyte and macrophage. MCAF plays an important role in inflammation, angiogenesis, auto-immune diseases, renal diseases, chronic infection and granuloma formation.Synonyms: C-C motif chemokine 2, HC-11, HC11, MCAF, MCP-1, Monocyte chemoattractant protein 1, Monocyte chemotactic and activating factor, Monocyte chemotactic protein 1, Monocyte secretory protein JE, SCYA2, Small-inducible cytokine A2

Gen-ID: 9606

UniProt: P13500

Pathways: Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, ER-Nucleus Signaling, Unfolded Protein Response, Phosphorylierungen bei SARS-CoV-2 Infektion