GM-CSF Antikörper

Produktnummer ABIN114524

Der Maus Monoklonal anti-GM-CSF Antikörper wird verwendet zum Nachweis von GM-CSF in Proben von Human. Er wurde validiert für WB und ELISA (Capture).

Kurzübersicht für GM-CSF Antikörper (ABIN114524)

Target: GM-CSF (CSF2) (Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser GM-CSF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA (Capture)

Klon: 59

Produktdetails anti-GM-CSF Antikörper

Spezifität: This monoclonal antibody reacts with natural and recombinant Human GM-CSF. Does not show any cross reaction with other Human Cytokines or Growth Factors tested such as M-CSF, G-CSFR, IL-8, IL-16, IL1-beta, TGF beta-1 and TNF-alpha.

Aufreinigung: Affinity Chromatography on Protein G.

Immunogen: Purified recombinant human GM-CSF Mouse IgG1.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: This antibody can be used as a capture antibody in sandwich ELISA applications forhuman GM-CSF detection in combination with a monoclonal tracer/detection antibody. Suggested Capture Coating Dose: 0.3 μg/well, Substrate: TMB. If the above suggestedconditions are followed approximately 2 pg/mL of GM-CSF in serum/plasma or medium canbe detected with an assay range of 0-500 pg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore with double distillated water to adjust the final concentration to 1.00 mg/mL

Konzentration: 1.0 mg/mL

Buffer: 0.01 M PBS, pH 7.2 without preservatives.

Konservierungsmittel: Without preservative

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Details zu GM-CSF

Target: GM-CSF (CSF2) (Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2))

Andere Bezeichnung: GM-CSF

Hintergrund: The cytokine GM-CSF stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. Used in myeloid reconstitution following bone marrow transplant, bone marrow transplant engraftment failure or delay, mobilization and following transplantation of autologous peripheral blood progenitor cells, and following induction chemotherapy in older adults with acute myelogenous leukemia.Synonyms: CSF2, Colony stimulating factor 2, GMCSF, Granulocyte-macrophage colony-stimulating factor, Molgramostin, Sargramostim

Gen-ID: 1437

NCBI Accession: NP_000749

UniProt: P04141

Pathways: JAK-STAT Signalweg, Cellular Response to Molecule of Bacterial Origin