CX3CL1 Antikörper (C-Term)

Produktnummer ABIN113336

Der Huhn Polyklonal Anti-CX3CL1-Antikörper wurde für IHC (fro) validiert. Er ist geeignet, CX3CL1 in Proben von Human, Ratte und Maus zu detektieren.

Kurzübersicht für CX3CL1 Antikörper (C-Term) (ABIN113336)

Target: CX3CL1 (Chemokine (C-X3-C Motif) Ligand 1 (CX3CL1))

Reaktivität: Human, Ratte, Maus

Wirt: Huhn

Klonalität: Polyklonal

Konjugat: Dieser CX3CL1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-CX3CL1 Antikörper

Bindungsspezifität: C-Term

Spezifität: The antibody reacts with Fractalkine.

Kreuzreaktivität (Details): Species reactivity (tested):Human, Mouse, Rat.

Aufreinigung: Affinity purified against peptide coupled to Sepharose

Immunogen: Synthetic C-terminal peptide coupled to carrier protein Remarks: The immunizing sequence is > 90% identical with the corresponding mouse and rat sequences.

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry on frozen sections: 1 μg/mL (1: 200). Lower working concentrationcombined with longer incubation time (e. g. > 2 hours at room temperature) and choice ofblocking reagent and secondary antibody may improve your results. Recommended positive control: Rat brain
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore with 0.5 mL distilled water to make stock solution.

Konzentration: 0.2 mg/mL

Buffer: PBS, pH 7.2 containing 0.01 % Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8 °C after reconstitution.

Details zu CX3CL1

Target: CX3CL1 (Chemokine (C-X3-C Motif) Ligand 1 (CX3CL1))

Andere Bezeichnung: Fractalkine / CX3CL1

Hintergrund: Fractalkine is a chemokine present in endothelial cells from several tissues, including brain, liver, and kidney. A high level of fractalkine has also been described in neurons from different regions of the mouse brain. It is the only member of the CX(3)C class of chemokines. Fractalkine contains a chemokine domain (CDF) attached to a membranespanning domain via a mucin-like stalk. However, fractalkine can also be proteolytically cleaved from its membrane-spanning domain to release a freely diffusible form. Fractalkine attracts and immobilizes leukocytes by binding to its receptor, CX(3)CR(1).Synonyms: C-X3-C motif chemokine 1, CX3C membrane-anchored chemokine, FKN, NTT, Neurotactin, SCYD1, Small-inducible cytokine D1

Gen-ID: 6376

NCBI Accession: NP_002987

UniProt: P78423

Pathways: Synaptic Membrane