C5 Antikörper

Produktnummer ABIN113312

Der Schaf Polyklonal Anti-C5-Antikörper wurde für IHC (fro) und ID validiert. Er ist geeignet, C5 in Proben von Human zu detektieren.

Kurzübersicht für C5 Antikörper (ABIN113312)

Target: C5 (Complement Component 5 (C5))

Reaktivität: Human

Wirt: Schaf

Klonalität: Polyklonal

Konjugat: Dieser C5 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunodiffusion (ID)

Produktdetails anti-C5 Antikörper

Spezifität: Gives a single arc when tested by IEP against fresh Human plasma. Identity has been confirmed by Double Diffusion against fresh Human plasma and a known anti-Human C5.

Aufreinigung: Ion Exchange Chromatography

Immunogen: Human C5 purified from plasma

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry: 1/20-1/200 (as a guide). Immunodiffusion.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Glycine buffered saline, pH 7.4, containing 0.09 % Sodium Azide, 0.1 % EACA, 0.01 % Benzamidine and 1 mM EDTA

Konservierungsmittel: Sodium azide, Benzamidine, EACA

Vorsichtsmaßnahmen: This product contains Sodium azide, Benzamidine and EACA: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid multiple freeze/thaw cycles.

Details zu C5

Target: C5 (Complement Component 5 (C5))

Andere Bezeichnung: Complement C5

Hintergrund: C5 is synthesised in the liver as a single polypeptide chain. Before secretion the molecule is glycosylated and secreted into plasma as a 190 kDa glycoprotein consisting of a disulphide linked alpha-chain (111 kDa) and beta-chain (75 kDa). C5 precursor is first processed by the removal of 4 basic residues, forming two chains, beta and alpha, linked by a disulfide bond. C5 convertase activates C5 by cleaving the alpha chain, releasing C5a anaphylatoxin and generating C5b (beta chain + alpha' chain).Synonyms: C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4, CPAMD4, Complement component 5

Gen-ID: 727

NCBI Accession: NP_001726

UniProt: P01031

Pathways: Komplementsystem, Carbohydrate Homeostasis