APOC1 Antikörper

Produktnummer ABIN113010

Dieses Anti-APOC1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von APOC1 in WB und EIA. Geeignet für Human.

Kurzübersicht für APOC1 Antikörper (ABIN113010)

Target: APOC1 (Apolipoprotein C-I (APOC1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser APOC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-APOC1 Antikörper

Spezifität: The antibody recognizes Apo CI. No cross-reactions with Apo AI, Apo AII, Apo B-100, Apo CII, Apo CIII, and Apo E.

Aufreinigung: Human Apo-CI-Sepharose affinity column

Immunogen: Human Apo-CI

Anwendungsinformationen

Applikationshinweise: Can be used for detection of Apo CI in plasma and lipoproteins, for immunoassay,immunoblot, enzyme conjugation, or biotinylation. Recommended dilutions: Immunoblot (1: 200-1: 5,000). ELISA (1: 5,000-1: 20,000). Successful use in immunohistochemistry on frozen sections was reported by someresearchers. As this detection method has not been verified by antibodies-online, theapplication was deleted from the database. This does not necessarily exclude the use insuch procedure.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL (OD280, E0.1% = 1.35)

Buffer: 75 mM PBS, 75 mM NaCl, pH 7.2 containig 1 mM EDTA and 0.02 % sodium azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in alqiuots) -20 °C for longer.

Details zu APOC1

Target: APOC1 (Apolipoprotein C-I (APOC1))

Andere Bezeichnung: Apolipoprotein C I (Apo CI)

Hintergrund: The protein encoded by this gene is a member of the apolipoprotein C1 family. This gene is expressed primarily in the liver, and it is activated when monocytes differentiate into macrophages. A pseudogene of this gene is located 4 kb downstream in the same orientation, on the same chromosome. This gene is mapped to chromosome 19, where it resides within a apolipoprotein gene cluster. Alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. Apolipoprotein C-I appears to modulate the interaction of APOE with beta migrating VLDL and inhibit binding of beta VLDL to the LDL receptor related protein.Synonyms: Apo-CI, Ap °C-I, Ap °C1, Apolipoprotein C-I, Apolipoprotein C1

Gen-ID: 341

NCBI Accession: NP_001636

UniProt: P02654

Pathways: Apoptose