Myeloperoxidase Antikörper
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- Target Alle Myeloperoxidase (MPO) Antikörper anzeigen
- Myeloperoxidase (MPO)
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Myeloperoxidase Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Aufreinigung
- Ammonium sulfate precipitation and DEAE-Sephacel ion exchange chromatography.
- Immunogen
- Neutrophil Myeloperoxidase
- Top Product
- Discover our top product MPO Primärantikörper
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- Applikationshinweise
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ELISA (>1: 4,000) and western blotting (1: 4,000 dilution gives a strong reaction to 0.3 and0.6 g antigen).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1.07 mg/mL (OD280 nm, E0.1% = 1.4).
- Buffer
- PBS, pH 7.4, with 0.09 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- Myeloperoxidase (MPO)
- Andere Bezeichnung
- Myeloperoxidase (MPO Produkte)
- Synonyme
- mKIAA4033 antikoerper, MPO antikoerper, LOC100335032 antikoerper, POX2' antikoerper, XPOX2' antikoerper, mpo antikoerper, mpo-A antikoerper, pmr-1 antikoerper, pmr1 antikoerper, pox2 antikoerper, xpox2 antikoerper, myeloperoxidase antikoerper, myeloperoxidase L homeolog antikoerper, MPO antikoerper, Mpo antikoerper, LOC100335032 antikoerper, mpo.L antikoerper
- Hintergrund
- Myeloperoxidase is a hemoprotein that is abundantly expressed in neutrophils and secreted during their activation. Native Myeloperoxidase is represented as a covalently bound tetrameric complex of two glycosylated alpha chains (MW 59 - 64 kDa) and two unglycosylated beta chains (MW 14 kDa) with total MW 150 kDa and theoretical pI 9.2. Traditionally Myeloperoxidase was considered as a main target of anti-neutrophil cytoplasm antibodies (ANCA), the serological markers for certain systemic vasculities e.g. periarteriitis nodosa, microscopic polyarteriitis and pulmonary eosinophilic granulomatosis (Churg-Strauss syndrome). Low to moderate anti-Myeloperoxidase autoantibody levels are also reported in rheumatoid arthritis. Recently it was shown that Myeloperoxidase participates in the initiation and progression of cardiovascular disease. It possesses potent proinflammatory properties and may contribute directly to tissue injury. Now Myeloperoxidase is under consideration as one of the most promising cardiac markers.Synonyms: MPO
- Gen-ID
- 9606
- UniProt
- P05164
- Pathways
- Chromatin Binding
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