CTXB Antikörper (HRP)

Produktnummer ABIN112703

Produktdetails anti-CTXB Antikörper (HRP)

Target: CTXB (CtxB Gene Product (CTXB))

Reaktivität: Vibrio cholerae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CTXB Antikörper ist konjugiert mit HRP

Applikation: Enzyme Immunoassay (EIA), Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))

Spezifität: This antibody detects the beta subunit of Cholera toxin.

Immunogen: Purified Choleragenoid.

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry on frozen sections (1: 20 - 1: 200). ELISA (1: 200 - 1: 1000). Western blot (1: 20 - 1: 200).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1-2 mg/mL

Buffer: Phosphate buffered saline, pH 7.2, containing 0.002 % Thimerosal and 1 % Bovine serum albumin

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu CTXB

Target: CTXB (CtxB Gene Product (CTXB))

Andere Bezeichnung: Cholera Enterotoxin Subunit B (CTXB Produkte)

Hintergrund: The Beta subunit of cholera toxin binds to a GM1-ganglioside receptor which is widely accepted to initiate toxin action by triggering uptake and delivery of the toxin Alpha subunit into cells. The holotoxin consists of a pentameric ring of Beta subunits whose central pore is occupied by the Alpha subunit. The Alpha subunit contains two chains, A1 and A2, linked by a disulfide bridge. The Alpha subunit (and Cholera toxin) activate the adenylate cyclase enzyme in cells of the intestinal mucosa leading to increased levels of intracellular cAMP.Synonyms: Cholera enterotoxin B chain, Cholera enterotoxin gamma chain, Choleragenoid, VC_1456, ctxB, toxB

Gen-ID: 2613962

NCBI Accession: NP_231099

UniProt: P01556