CTXB Antikörper

Produktnummer ABIN112701

Der Kaninchen Polyklonal anti-CTXB Antikörper (ABIN112701) detektiert spezifisch CTXB in EIA, IHC (fro), IP und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Vibrio cholerae.

Kurzübersicht für CTXB Antikörper (ABIN112701)

Target: CTXB (CtxB Gene Product (CTXB))

Reaktivität: Vibrio cholerae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CTXB Antikörper ist unkonjugiert

Applikation: Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Immunofluorescence (IF)

Produktdetails anti-CTXB Antikörper

Spezifität: Reacts with the beta subunit of Cholera Toxin.

Aufreinigung: Ig Fraction

Immunogen: Purified choleragenoid

Anwendungsinformationen

Applikationshinweise: ELISA. Immunoprecipitation. Has been described to work in Immunohistochemistry on Frozen Sections andImmunofluorescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: PBS, pH 7.2 containing 0.09 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu CTXB

Target: CTXB (CtxB Gene Product (CTXB))

Andere Bezeichnung: Cholera Enterotoxin Subunit B

Hintergrund: The beta subunit of cholera toxin binds to a GM1-anglioside receptor which is widely accepted to initiate toxin action by triggering uptake and delivery of the toxin alpha subunit into cells. The holotoxin consists of a pentameric ring of beta subunits whose central pore is occupied by the alpha subunit. The alpha subunit contains two chains, A1 and A2, linked by a disulfide bridge. The alpha subunit (and cholera toxin) activate the adenylate cyclase enzyme in cells of the intestinal mucosa leading to increased levels of intracellular cAMP.Synonyms: Cholera enterotoxin B chain, Cholera enterotoxin gamma chain, Choleragenoid, VC_1456, ctxB, toxB

Gen-ID: 2613962

NCBI Accession: NP_231099

UniProt: P01556