ENO1 Antikörper

Produktnummer ABIN112663

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch ENO1 in WB, IHC (p), EIA und IHC (fro). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für ENO1 Antikörper (ABIN112663)

Target: ENO1 (Enolase 1 (ENO1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ENO1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-ENO1 Antikörper

Spezifität: This antibody detects Human Non-Neuronal Enolase, and demostrates less than 0.1 % cross-reactivity with non-specific Enolase.

Aufreinigung: Affinity Chromatography on Protein G

Immunogen: Native Human NNE.

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry on Frozen and Paraffin Sections (each 1/25-1/100). ELISA. Western blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 5.0 mg/mL (by OD 280 nm)

Buffer: PBS, 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu ENO1

Target: ENO1 (Enolase 1 (ENO1))

Andere Bezeichnung: alpha-Enolase (ENO1)

Hintergrund: Non Neuronal Enolase (ENO1) is an isoform of mammalian enolase and is composed of 2 alpha subunits. The gene for ENO1 encodes alpha-enolase, a homodimeric soluble enzyme, and also encodes a shorter monomeric structural lens protein, tau-crystallin. The two proteins are made from the same message. The full length protein, the isoenzyme, is found in the cytoplasm. The shorter protein is produced from an alternative translation start, is localized to the nucleus, and has been found to bind to an element in the c-myc promoter. Non Neuronal Enolase can be as a diagnostic marker for many tumors, as a marker for endometriosis and in the heterodimeric form, alpha/gamma, as a marker for hypoxic brain injury after cardiac arrest. It has been identified as an autoantigen in Hashimoto encephalopathy (associated with Hashimoto thyroiditis).Synonyms: 2-phospho-D-glycerate hydro-lyase, C-myc promoter-binding protein, ENO1L1 Non-neural enolase, Enolase 1, MBP-1, MBPB1, MPB-1, MPB1, NNE, Phosphopyruvate hydratase, Plasminogen-binding protein

Gen-ID: 2023

NCBI Accession: NP_001188412

UniProt: P06733