ENO1 Antikörper (Middle Region)

Produktnummer ABIN2775758

Produktdetails anti-ENO1 Antikörper

Target: ENO1 (Enolase 1 (ENO1))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Zebrafisch (Danio rerio), Kaninchen, Meerschweinchen, Pferd, Hund, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ENO1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: VAASEFFRSG KYDLDFKSPD DPSRYISPDQ LADLYKSFIK DYPVVSIEDP

Homologie: Cow: 79%, Dog: 93%, Guinea Pig: 93%, Horse: 79%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against ENO1. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ENO1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 434 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-ENO1 Antikörper (ABIN2775758)

Braceland, McLoughlin, Tinsley, Wallace, Cockerill, McLaughlin, Eckersall: "Serum enolase: a non-destructive biomarker of white skeletal myopathy during pancreas disease (PD) in Atlantic salmon Salmo salar L." in: Journal of fish diseases, Vol. 38, Issue 9, pp. 821-31, (2015) (PubMed).

Kitahashi, Yoshimoto, Imai: "Novel immunohistochemical marker, integrin ?(V)?(3), for BOP-induced early lesions in hamster pancreatic ductal carcinogenesis." in: Oncology letters, Vol. 2, Issue 2, pp. 229-234, (2012) (PubMed).

Deng, Lam, Meyer, Feldon, Li, Wei, Luk, Chua, Sham, Wang, McAlonan: "Frontal-subcortical protein expression following prenatal exposure to maternal inflammation." in: PLoS ONE, Vol. 6, Issue 2, pp. e16638, (2011) (PubMed).

Sørensen, Horsman, Vorum, Honoré, Overgaard, Alsner: "Proteins upregulated by mild and severe hypoxia in squamous cell carcinomas in vitro identified by proteomics." in: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, Vol. 92, Issue 3, pp. 443-9, (2009) (PubMed).

Boraldi, Annovi, Carraro, Naldini, Tiozzo, Sommer, Quaglino: "Hypoxia influences the cellular cross-talk of human dermal fibroblasts. A proteomic approach." in: Biochimica et biophysica acta, Vol. 1774, Issue 11, pp. 1402-13, (2007) (PubMed).

Details zu ENO1

Target: ENO1 (Enolase 1 (ENO1))

Andere Bezeichnung: ENO1 (ENO1 Produkte)

Synonyme: enolase 1 antikoerper, F2P9.10 antikoerper, F2P9_10 antikoerper, Pgh1 antikoerper, pENO1 antikoerper, enolase 1 antikoerper, phosphopyruvate hydratase antikoerper, ENO1 antikoerper, eno1 antikoerper

Hintergrund: ENO1 encodes one of three enolase isoenzymes found in mammals, it encodes alpha-enolase, a homodimeric soluble enzyme, and also encodes a shorter monomeric structural lens protein, tau-crystallin. The two proteins are made from the same message. The full length protein, the isoenzyme, is found in the cytoplasm. The shorter protein is produced from an alternative translation start, is localized to the nucleus, and has been found to bind to an element in the c-myc promoter. A pseudogene has been identified that is located on the other arm of the same chromosome.
Alias Symbols: NNE, PPH, MPB1, ENO1L1
Protein Interaction Partner: UBC, FUS, HUWE1, ISG15, SUMO2, SUMO3, IVNS1ABP, STAU1, MDM2, WWOX, EED, FBXO6, UPF2, YWHAQ, UBD, TERT, SRC, RAD52, NPM1, BHLHE40, VCAM1, HCVgp1, ITGA4, FN1, ATF2, SERPING1, AMBP, LIG4, BRCA1, MDC1, PGK1, ITPA, GAPDH, FYN, FLNC, ENO3, Htt, TPI1, PPIA, AKT1
Protein Size: 434

Molekulargewicht: 47 kDa

Gen-ID: 2023

NCBI Accession: NM_001428, NP_001419

UniProt: Q53HR3