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CGRP Antikörper (AA 23-37)

CALCA Reaktivität: Ratte, Maus, Reptile IHC (p), IF, EIA Wirt: Ziege Polyclonal unconjugated
Produktnummer ABIN112616
  • Target Alle CGRP (CALCA) Antikörper anzeigen
    CGRP (CALCA) (Calcitonin-Related Polypeptide alpha (CALCA))
    Bindungsspezifität
    • 15
    • 7
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 23-37
    Reaktivität
    • 67
    • 38
    • 11
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    Ratte, Maus, Reptile
    Wirt
    • 60
    • 18
    • 5
    • 2
    • 2
    • 1
    Ziege
    Klonalität
    • 69
    • 18
    Polyklonal
    Konjugat
    • 58
    • 7
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CGRP Antikörper ist unkonjugiert
    Applikation
    • 55
    • 39
    • 29
    • 13
    • 13
    • 10
    • 9
    • 8
    • 8
    • 7
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Spezifität
    Recognizes Calcitonin gene-related peptide, also known as CGRP, a neuropeptide that acts as a vasodilator and may play a role in migraine. This antibody is reactive with both whole molecule (1-37) and the C-terminal (23-37). Specifically visualises CGRP in brain cells.
    Aufreinigung
    Affinity Chromatography on Protein G
    Immunogen
    Synthetic Rat Tyr-CGRP (23-37) conjugated to gamma globulin
    Isotyp
    IgG
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    Discover our top product CALCA Primärantikörper
  • Applikationshinweise
    ELISA (1/500-1/2500). Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    5.0 mg/mL
    Buffer
    PBS containing 0.09 % Sodium Azide as preservative
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    CGRP (CALCA) (Calcitonin-Related Polypeptide alpha (CALCA))
    Andere Bezeichnung
    CGRP / CALCA (CALCA Produkte)
    Synonyme
    CALC1 antikoerper, CGRP antikoerper, CGRP-I antikoerper, CGRP1 antikoerper, CT antikoerper, KC antikoerper, CALC antikoerper, CALCA antikoerper, CALC3 antikoerper, ci-ct antikoerper, calca antikoerper, CA antikoerper, CGRP-1 antikoerper, Calc antikoerper, Calc1 antikoerper, Cgrp antikoerper, Ct antikoerper, Ctn antikoerper, calcitonin antikoerper, CAL6 antikoerper, Cal1 antikoerper, RATCAL6 antikoerper, CGRPI antikoerper, calc antikoerper, cgrp antikoerper, zgc:92886 antikoerper, calcitonin related polypeptide alpha antikoerper, calcitonin related polypeptide beta antikoerper, calcitonin-related polypeptide alpha antikoerper, calcitonin antikoerper, calcitonin/calcitonin-related polypeptide, alpha antikoerper, calcitonin-related polypeptide beta antikoerper, calcitonin gene-related peptide 2 antikoerper, CALCA antikoerper, CALCB antikoerper, ci-ct antikoerper, calca antikoerper, Calca antikoerper, LOC100008771 antikoerper
    Hintergrund
    CGRP is present in C-cells of the thyroid and in central and peripheral nerves. CGRP has several important physiologic roles: it is a potent vasodilator, and can affect the force and rate of heart beat, it can modulate acetylcholine receptor function at the neuromuscular junction, it has been demonstrated to block tolerance to morphine, and it can modulate antigen presentation in Langerhans cells in the skin. Despite these important physiologic functions, therapeutic strategies using CGRP have been impeded due to the lack of a cloned CGRP receptor with which ligands could be developed.Synonyms: Alpha-type CGRP, CALC1, CGRP-I, Calcitonin gene-related peptide I
    Gen-ID
    24241
    NCBI Accession
    NP_001029127
    UniProt
    P01256
    Pathways
    Hormone Activity, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development, Feeding Behaviour
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