Tissue factor Antikörper
Kurzübersicht für Tissue factor Antikörper (ABIN112492)
Target
Alle Tissue factor (F3) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- This antibody is specific for an epitope within the extracellular domain, epitope locus I. It recognizes both the reduced and native non-reduced human and primate tissue factors. It does not inhibit coagulation or neutralize factor VII binding to CD142.
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Aufreinigung
- Affinity Chromatography on Protein G.
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Immunogen
- Denatured Tissue factor isolated from human brain by the Factor VII affinity method.
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Isotyp
- IgG1
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Applikationshinweise
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ELISA. Western blot. Flow Cytometry. Immunofluorescence. Immunohistology on Frozen and Paraffin Sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1.0 mg/mL
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Buffer
- Phosphate buffered saline containing 0.09 % Sodium Azide as preservative and 200 mM Mannitol as stabilizer.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Tissue factor (F3) (Coagulation Factor III (thromboplastin, Tissue Factor) (F3))
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Andere Bezeichnung
- CD142 / Tissue Factor
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Hintergrund
- CD142, also known as Tissue factor, is the membrane receptor for coagulation factors VII and VIIa and is the cell surface initiator of coagulation. It is the major molecule of this type and is criticial for controlling hemostasis, thrombosis and inflammation.Synonyms: Coagulation factor III, F3, TF, Thromboplastin
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Gen-ID
- 2152
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NCBI Accession
- NP_001984
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UniProt
- P13726
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Pathways
- Positive Regulation of Endopeptidase Activity, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
Target
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