ITGB1 Antikörper (C-Term, N-Term)

Produktnummer ABIN112374

Der Maus Monoklonal anti-ITGB1 Antikörper (Klon 2B1) (ABIN112374) detektiert spezifisch ITGB1 in WB, IF und IHC (fro). Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Schwein und Hund.

Kurzübersicht für ITGB1 Antikörper (C-Term, N-Term) (ABIN112374)

Target: ITGB1 (Integrin beta 1 (ITGB1))

Reaktivität: Human, Maus, Schwein, Hund

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ITGB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: 2B1

Produktdetails anti-ITGB1 Antikörper

Bindungsspezifität: C-Term, N-Term

Sequenz: CQENPIYKS-PINNFKNPNY GRKAGL

Aufreinigung: Purified

Immunogen: A synthetic peptide corresponding to the C-terminal 24 amino acids of integrin b1D including an appending N-terminal cysteine coupled to keyhole limpet hemocyanin.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Immunoblotting: 1: 100 - 1: 1000. Immunocytochemistry. Immunohistochemistry on frozen tissue: 1/25 -1/200 with an ABC method.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS with 0.09 % Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store undiluted (in aliquots) at -20 °C.

Details zu ITGB1

Target: ITGB1 (Integrin beta 1 (ITGB1))

Andere Bezeichnung: CD29 / Integrin beta-1

Hintergrund: Integrins are a family of heterodimeric membrane glycoproteins consisting of non-covalently associated alpha and beta subunits. More than 18 alpha and 8 beta subunits with numerous splice variant isoforms have been identified in mammals. In general, integrins function as receptors for extracellular matrix proteins. Certain integrins can also bind to soluble ligands or to counter-receptors on adjacent cells, such as the intracellular adhesion molecules (ICAMs), resulting in aggregation of cells. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis. There are two major forms of integrin beta1: beta1A and beta1D, which differ in 13 amino acids. Their distribution pattern in adult tissues is mutually exclusive. bea1A is present in all tissues, except cardiac and skeletal muscle, which instead express the beta1D variant.Synonyms: FNRB, Fibronectin receptor subunit beta, ITGB1, Integrin VLA-4 subunit beta, MDF2, MSK12

Gen-ID: 9606

UniProt: P05556

Pathways: Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex, SARS-CoV-2 Protein Interaktom