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CD31 Antikörper

Name: CD31 Antikörper
SKU: ABIN111927
Price: 616.63 EUR
Availability: InStock

PECAM1 Reaktivität: Human FACS, WB Wirt: Maus Monoclonal MEM-05 unconjugated

(1 reference)

Produktnummer ABIN111927

Datenblatt (PDF)

Target Alle CD31 (PECAM1) Antikörper anzeigen

CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))
Reaktivität
270

149

75

59

44

31

21

20

11

7

4

4

4

1

1

1
Human
Wirt
164

140

54

8

6

3

2
Maus
Passende Sekundärantikörper
Klonalität
241

127

8

1
Monoklonal
Konjugat
163

33

31

25

13

6

6

5

5

5

5

5

5

5

5

5

4

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1
Dieser CD31 Antikörper ist unkonjugiert
Applikation
240

180

106

101

63

39

37

34

33

26

21

15

13

12

9

6

4

3

3

2

2

2

2

1

1

1

1

1
Flow Cytometry (FACS), Western Blotting (WB)

Kreuzreaktivität (Details)

Species reactivity (tested):Human

Aufreinigung

Affinity Chromatography on Protein A

Immunogen

Leucocytes of patient suffering from LGL-type leukaemia

Klon

MEM-05

Isotyp

IgG1

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anti-Platelet/endothelial Cell Adhesion Molecule (PECAM1) (AA 681-738) antibody
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PECAM1 Reaktivität: Human WB, ELISA, IP, IHC (p) Wirt: Maus Monoclonal 1D2-1A5 unconjugated

anti-Platelet/endothelial Cell Adhesion Molecule (PECAM1) antibody
PECAM1 Reaktivität: Human, Kaninchen, Cynomolgus FACS, WB, IHC, IF, StM Wirt: Maus Monoclonal JC-70A unconjugated

anti-Platelet/endothelial Cell Adhesion Molecule (PECAM1) antibody
PECAM1 Reaktivität: Human, Ratte, Kaninchen, Cynomolgus FACS, WB, IHC, StM Wirt: Maus Monoclonal C31-7 unconjugated

anti-Platelet/endothelial Cell Adhesion Molecule (PECAM1) (AA 625-738) antibody
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anti-Platelet/endothelial Cell Adhesion Molecule (PECAM1) antibody
PECAM1 Reaktivität: Human, Ratte FACS, WB, IHC, IF, StM Wirt: Maus Monoclonal C31-3 unconjugated

Applikationshinweise

Flow Cytometry. Western Blotting under non reducing conditions.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Konzentration

1.0 mg/mL

Buffer

Phosphate buffered saline (PBS) with 15 mM Sodium Azide, approx. pH 7.4

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung

Avoid repeated freezing and thawing.

Lagerung

4 °C/-20 °C

Informationen zur Lagerung

Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Soupene, Serikov, Kuypers: "Characterization of an acyl-coenzyme A binding protein predominantly expressed in human primitive progenitor cells." in: Journal of lipid research, Vol. 49, Issue 5, pp. 1103-12, (2008) (PubMed).
Target

CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

Andere Bezeichnung

CD31 / PECAM1 (PECAM1 Produkte)

Hintergrund

CD31 (platelet endothelial cell adhesion molecule-1, PECAM-1) is an inhibitory coreceptor involved in rebulation of T cell and B cell signaling by a dual immunoreceptor tyrosine-based inhibitory motif (ITIM) that upon associated kinases-mediated phosphorylation provide docking sites for protein-tyrosine phosphatases. CD31 is expressed ubiquitously within the vascular compartment and is located mainly at junctions between adjacent cells. N-terminal Ig-like domain of CD31 is responsible for its homophilic binding, which plays an important role in cell-cell interactions. CD31 is a multifunctional molecule with diverse roles in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, negative regulation of immunoreceptor signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. It is one of key regulatory molecules in vascular system.Synonyms: End °CAM, GPIIA', PECAM-1, Platelet endothelial cell adhesion molecule

Gen-ID

9606

UniProt

P16284

Pathways

Regulation of Actin Filament Polymerization