beta Endorphin Antikörper

Produktnummer ABIN111317

Der Maus Monoklonal anti-beta Endorphin Antikörper wird verwendet zum Nachweis von beta Endorphin in Proben von Human. Er wurde validiert für IHC (fro), IHC (p) und IF.

Kurzübersicht für beta Endorphin Antikörper (ABIN111317)

Target: beta Endorphin (beta-EP) (Endorphin beta (beta-EP))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser beta Endorphin Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Klon: B31-15

Produktdetails anti-beta Endorphin Antikörper

Aufreinigung: Affinity chromatography on Protein A

Immunogen: Human beta endorphin (full length native protein).

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Immunofluorescence. Immunohistochemistry on frozen sections. Immunohistochemistry on paraffin sections: Microwave pretreatment is recommended. Recommended positive Control: Human pituitary gland.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu beta Endorphin

Target: beta Endorphin (beta-EP) (Endorphin beta (beta-EP))

Andere Bezeichnung: beta Endorphin

Hintergrund: Beta-Endorphin is an endogenous opioid peptide neurotransmitter found in the neurons of both the central and peripheral nervous system. Beta-Endorphin is a peptide, 31 amino acids long, resulting from processing of the precursor pro-opiomelanocortin (POMC). Beta-Endorphin is found in neurons of the hypothalamus as well as the pituitary gland. It is an agonist of the opioid receptors, with evidence suggesting that it serves as the endogenous ligand of the μ-opioid receptor, the same receptor to which the chemicals extracted from opium, such as morphine and codeine, have their analgesic and addictive effects. Beta-Endorphin occurs in cells in the anterior pituitary. Beta-Endorphin may be detected in tumors of the pituitary, gastroinestinal and bronchial carcinoids. Absorption with 10-100 μg beta-Endorphin per ml diluted antiserum inactivates the antiserum, while Beta-lipotropin, met-enkephalin and leu-enkephalin do not.Synonyms: Endorfin-beta, Endorphin-beta

Pathways: Metabolism of Steroid Hormones and Vitamin D, Peptide Hormone Metabolism, Hormone Activity