TIE1 Antikörper

Produktnummer ABIN1112934

Dieses Anti-TIE1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von TIE1 in WB, ICC und FACS. Geeignet für Maus und Ratte.

Kurzübersicht für TIE1 Antikörper (ABIN1112934)

Target: TIE1 (tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TIE1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Produktdetails anti-TIE1 Antikörper

Aufreinigung: affinity purified

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB (1:5000), ICC (1:100-500), Flow Cyt (1:10-100). Other applications have not been tested. The optimal dilutions should be determined by end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: TBS (pH7.4), 0.5% BSA, 40% Glycerol and 0.05% Sodium Azide.

Konservierungsmittel: Sodium azide, Thimerosal (Merthiolate)

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C after thawing (1 week). Aliquot and store at -20 °C for long term (at least one year). Avoid repeated freeze and thaw cycles.

Haltbarkeit: 12 months

Details zu TIE1

Target: TIE1 (tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1))

Andere Bezeichnung: Tyrosine-Protein Kinase Receptor TIE1

Hintergrund: Tyrosine kinase with immunoglobulin-like and EGF-like domains 1, TIE1 is an angiopoietin receptor which in humans is encoded by the TIE1 gene. 1 The receptor tyrosine kinase Tie1 is expressed in both vascular endothelial cells and immature hematopoietic cells. 2 TIE1 upregulates the cell adhesion molecules (CAMs) VCAM-1, E-selectin, and ICAM-1 through a p38-dependent mechanism. Attachment of monocyte derived immune cells to endothelial cells is also enhanced by TIE1 expression. TIE1 has a proinflammatory effect and may play a role in the endothelial inflammatory diseases such as atherosclerosis. 3

Pathways: RTK Signalweg