TdT Antikörper

Produktnummer ABIN1112828

Der Maus Monoklonal Anti-TdT-Antikörper wurde für WB validiert. Er ist geeignet, TdT in Proben von Human zu detektieren.

Kurzübersicht für TdT Antikörper (ABIN1112828)

Target: TdT (DNTT) (Deoxynucleotidyltransferase, terminal (DNTT))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TdT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: N153

Produktdetails anti-TdT Antikörper

Immunogen: A synthetic peptide (conjugated with KLH) corresponding to the C-terminal of human TDT.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: WB (1:1000). Other applications have not been tested. The optimal dilutions should be determined by end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: TBS (pH7.4), 0.5% BSA, 25% Glycerol and 0.05% Sodium Azide.

Konservierungsmittel: Sodium azide, Thimerosal (Merthiolate)

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C after thawing (1 week). Aliquot and store at -20 °C for long term (at least one year). Avoid repeated freeze and thaw cycles.

Haltbarkeit: 12 months

Details zu TdT

Target: TdT (DNTT) (Deoxynucleotidyltransferase, terminal (DNTT))

Andere Bezeichnung: Terminal deoxynucleotidyl transferase, TDT

Hintergrund: Terminal deoxynucleotidyl transferase (TdT), also known as DNA nucleotidylexotransferase (DNTT) or terminal transferase, is a DNA polymerase expressed in immature lymphocytes of the thymus and bone marrow, as well as certain leukemic cells. 1 TDT cDNA contains an open reading frame of 1530 base pairs (bp) corresponding to a protein containing 510 amino acids. 2 TDT is a useful marker in the diagnosis of acute lymphoblastic leukemia (ALL) (French-American-British [FAB] L1 and L2) and is most useful in distinguishing ALL from mature B-lymphoid neoplasms, such as Burkitt lymphoma (FAB L3) and other lymphoid malignancies. 3

Pathways: DNA Reparatur