Complement C3b Antikörper

Produktnummer ABIN1112803

Dieses Maus Monoklonal-Antikörper erkennt spezifisch Complement C3b in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Complement C3b Antikörper (ABIN1112803)

Target: Complement C3b (C3b) (Complement C3 beta Chain (C3b))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Complement C3b Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: S8-6

Produktdetails anti-Complement C3b Antikörper

Immunogen: A synthetic peptide (conjugated with KLH) corresponding to the region of human Complement C3-beta chain.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: WB (1:2000). Other applications have not been tested. The optimal dilutions should be determined by end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: TBS (pH7.4), 0.5% BSA, 40% Glycerol and 0.05% Sodium Azide.

Konservierungsmittel: Sodium azide, Thimerosal (Merthiolate)

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C after thawing (1 week). Aliquot and store at -20 °C for long term (at least one year). Avoid repeated freeze and thaw cycles.

Haltbarkeit: 12 months

Details zu Complement C3b

Target: Complement C3b (C3b) (Complement C3 beta Chain (C3b))

Andere Bezeichnung: Complement C3-beta Chain

Hintergrund: Complement component 3, often simply called C3, is a member of the complement system. The complement system is an important mediator of natural and acquired immunity. It consists of approximately 30 proteins that can exhibit catalytic activity, function as regulators, or act as cellular surface receptors. These components normally circulate in inactive forms and are activated by the classical, alternative, or lectin pathways. Complement component 3 plays a central role in all 3 activation pathways. People with C3 deficiency are susceptible to bacterial infection. Clinically, the Level of C3 in the blood may be measured to support or refute a particular medical diagnosis. For example, low C3 levels are associated with some types of kidney disease such as post-infectious glomerulonephritis and shunt nephritis.

Pathways: Komplementsystem, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Regulation of G-Protein Coupled Receptor Protein Signaling