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PRKDC Antikörper (Catalytic Subunit)

Name: PRKDC Antikörper (Catalytic Subunit)
SKU: ABIN1112714
Price: 501.6 EUR
Availability: InStock

Der Maus Monoklonal Anti-PRKDC-Antikörper wurde für WB, IHC, IHC (p) und ICC validiert. Er ist geeignet, PRKDC in Proben von Maus zu detektieren.

IHC (p)

Immunocytochemistry (ICC) image for anti-Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC) (Catalytic Subunit) antibody (ABIN1112714) (PRKDC Antikörper (Catalytic Subunit))

ICC

Image no. 3 for anti-Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC) (Catalytic Subunit) antibody (ABIN1112714) (PRKDC Antikörper (Catalytic Subunit))

3 Abbildungen

Produktnummer ABIN1112714

Kurzübersicht für PRKDC Antikörper (Catalytic Subunit) (ABIN1112714)

Target

Alle PRKDC Antikörper anzeigen

PRKDC (Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC))

Reaktivität

Maus

Wirt

Maus

Klonalität

Monoklonal

Konjugat

Dieser PRKDC Antikörper ist unkonjugiert

Applikation

Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Klon

Discover our top product PRKDC Primärantikörper

Bindungsspezifität
26

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Catalytic Subunit

Immunogen

Recombinant DNA-PKcs protein.

Isotyp

IgG2a
anti-Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC) antibody
PRKDC Reaktivität: Human ELISA, IHC, ICC Wirt: Maus Monoclonal 3H6 unconjugated

anti-Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC) (AA 4019-4128) antibody
PRKDC Reaktivität: Human ELISA, WB, IF, IHC (p) Wirt: Maus Monoclonal 1B9 unconjugated

anti-Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC) antibody
PRKDC Reaktivität: Human WB, IHC, IP, ICC Wirt: Maus Monoclonal unconjugated

anti-Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC) (C-Term) antibody
PRKDC Reaktivität: Human, Maus ELISA, WB, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC) (C-Term) antibody
PRKDC Reaktivität: Human ELISA, WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

anti-Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC) (AA 3899-4128) antibody
PRKDC Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC) (C-Term) antibody
PRKDC Reaktivität: Human, Maus ELISA, WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

anti-Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC) (AA 151-300) antibody
PRKDC Reaktivität: Human, Ratte ELISA, WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated

anti-Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC) (AA 4075-4104), (C-Term) antibody
PRKDC Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB3465-3466 unconjugated

anti-Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC) (AA 4019-4129) antibody
PRKDC Reaktivität: Human ELISA, WB, IHC, IHC (p) Wirt: Maus Monoclonal 2A8 unconjugated

Applikationshinweise

WB (1:1000), IHC-P (1:200), ICC (1:100). Other applications have not been tested. The optimal dilutions should be determined by end user.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

TBS (pH7.4), 0.5% BSA, 40% Glycerol and 0.05% Sodium Azide.

Konservierungsmittel

Sodium azide, Thimerosal (Merthiolate)

Lagerung

4 °C/-20 °C

Informationen zur Lagerung

Store at 4 °C after thawing (1 week). Aliquot and store at -20 °C for long term (at least one year). Avoid repeated freeze and thaw cycles.

Haltbarkeit

12 months
Target

PRKDC (Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC))

Hintergrund

DNA-dependent protein kinase, catalytic subunit, also known as DNA-PKcs, is an enzyme that belongs to the phosphatidylinositol 3-kinase-related kinase protein family. Anderson and Lees-Miller (1992) noted that DNA-PK had been shown in vitro to phosphorylate several transcription factors, suggesting that it functions in cell homeostasis by modulating transcription. It acts as a molecular sensor for DNA damage, and it may also act as a scaffold protein to aid the localization of DNA repair proteins to the site of damage.

Pathways

DNA Reparatur, Production of Molecular Mediator of Immune Response