POMC Antikörper (C-Term)

Produktnummer ABIN111034

Dieses Maus Monoklonal-Antikörper erkennt spezifisch POMC in IHC (p), IHC (fro) und EIA. Er zeigt eine Reaktivität gegenüber Human und Ratte.

Kurzübersicht für POMC Antikörper (C-Term) (ABIN111034)

Target: POMC (Proopiomelanocortin (POMC))

Reaktivität: Human, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser POMC Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Klon: 56

Produktdetails anti-POMC Antikörper

Bindungsspezifität: C-Term

Spezifität: Reacts with Human and Rat C-terminal ACTH. Specific for CLIP (17-39 ACTH) and does not cross-react with Synacthen (1-24 ACTH).

Aufreinigung: Protein A Chromatography

Immunogen: ACTH-BSA Conjugate Remarks:

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Reacts with solid phase ACTH either captured as part of a sandwich or adsorbed as a solidphase antigen and as such is suitable for serum assay development. Also reactive onformalin-fixed paraffin wax embedded tissue and is therefore suitable forimmunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu POMC

Target: POMC (Proopiomelanocortin (POMC))

Andere Bezeichnung: POMC

Hintergrund: ACTH occurs in cells of the anterior pituitary and in neurons in brain. It regulates the corticosteroid production in the adrenal cortex. Beta endorphin and Met enkephalin are endogenous opiates. MSH (melanocyte stimulating hormone) increases the pigmentation of skin by increasing melanin production in melanocytes.Synonyms: Adrenocorticotropic hormone, Corticotropin, POMC

Gen-ID: 5443

NCBI Accession: NP_000930

UniProt: P01189

Pathways: Metabolism of Steroid Hormones and Vitamin D, Peptide Hormone Metabolism, Hormone Activity, Feeding Behaviour