TUBB Antikörper (N-Term)

Produktnummer ABIN110979

Produktdetails anti-TUBB Antikörper

Target: TUBB (Tubulin, beta (TUBB))

Bindungsspezifität: N-Term

Reaktivität: Schwein

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TUBB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: The antibody recognizes an epitope (aa 81-95) on phylogenetically conserved N-terminal structural domain of beta-tubulin (recognizes all beta-tubulin isoforms) in various species.

Aufreinigung: Precipitation methods

Reinheit: > 95 % (by SDS-PAGE)

Immunogen: Beta-subunits of porcine brain tubulin

Klon: TU-06

Isotyp: IgM

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry (paraffin sections): 5 μg/mL, Positive tissue: heartImmunocytochemistry: 2 μg/mL. Staining technique: fixed and permeabilized cells.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Tris buffered saline (TBS) with 15 mM sodium azide, approx. pH 8.0

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Dilute only prior to immediate use

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody (undiluted) at 2-8 °C. DO NOT FREEZE! Freezing alkaline phosphatase conjugates will result in a substantial loss of enzymatic activity.

Details zu TUBB

Target: TUBB (Tubulin, beta (TUBB))

Andere Bezeichnung: TUBB / TUBB5 (TUBB Produkte)

Synonyme: M40 antikoerper, OK/SW-cl.56 antikoerper, TUBB1 antikoerper, TUBB5 antikoerper, XLOT antikoerper, m40 antikoerper, ok/sw-cl.56 antikoerper, tubb1 antikoerper, tubb5 antikoerper, TUBB2A antikoerper, TUBB2B antikoerper, TUBB antikoerper, 1t antikoerper, B1t antikoerper, BETA 56D antikoerper, CG9277 antikoerper, DTB2 antikoerper, Dmbeta1 antikoerper, Dmel\\CG9277 antikoerper, T antikoerper, Tub antikoerper, Tubulin antikoerper, beta antikoerper, beta-Tub antikoerper, beta-Tub56D antikoerper, beta-tub antikoerper, beta-tubulin56D antikoerper, beta1 antikoerper, beta1-Tubulin antikoerper, beta1-tub antikoerper, beta1Tub antikoerper, beta1t antikoerper, beta1tub antikoerper, beta56D antikoerper, betaTub antikoerper, betaTub1 antikoerper, beta[[1]] tubulin antikoerper, beta[[1]]-tubulin antikoerper, betatub(56D) antikoerper, 143391_i_at antikoerper, 3t antikoerper, B3t antikoerper, BETA 60D antikoerper, CG3401 antikoerper, D.m.BETA-60D antikoerper, DTB3 antikoerper, Dmbeta3 antikoerper, Dmel\\CG3401 antikoerper, Tub60D antikoerper, beta-Tub60D antikoerper, beta-Tub6D antikoerper, beta3 antikoerper, beta3 TU antikoerper, beta3-Tub antikoerper, beta3-tubulin antikoerper, beta3TUB antikoerper, beta3Tub antikoerper, beta3t antikoerper, beta60C antikoerper, betaTub3 antikoerper, betaTub60C antikoerper, beta[[3]] tubulin antikoerper, beta[[3]]-Tub antikoerper, beta[[3]]-tubulin antikoerper, betatub60D antikoerper, p50 antikoerper, p50/tubulin antikoerper, p53 antikoerper, p53/tubulin antikoerper, 2t antikoerper, B2t antikoerper, BETA 85D antikoerper, BETA2 antikoerper, CG9359 antikoerper, D.m.BETA-85D antikoerper, DTB4 antikoerper, Dmbeta2 antikoerper, Dmel\\CG9359 antikoerper, beta(2)Tu antikoerper, beta(2)Tub antikoerper, beta-Tub85D antikoerper, beta-tub85D antikoerper, beta2 antikoerper, beta2-tub antikoerper, beta2t antikoerper, beta2tub antikoerper, beta85D antikoerper, betaTub2 antikoerper, beta[[2]]-tubulin antikoerper, ms(3)KK[D] antikoerper, 4t antikoerper, B4t antikoerper, BETA 98B antikoerper, CG4869 antikoerper, DTB1 antikoerper, Dmbeta4 antikoerper, Dmel\\CG4869 antikoerper, beta-Tub97EF antikoerper, beta4 antikoerper, beta4t antikoerper, beta97F antikoerper, betaTub4 antikoerper, betaTub98BC antikoerper, betaTub98C antikoerper, Tub1 antikoerper, bmtub1 antikoerper, Tub3 antikoerper, bmtub3 antikoerper, Tub2 antikoerper, bmtub2 antikoerper, Tub4 antikoerper, bmtub4 antikoerper, LOC100101153 antikoerper, tubulin beta class I antikoerper, putative cobalt-zinc-cadmium outer membrane resistance protein antikoerper, Tubulin beta chain antikoerper, tubulin beta-2A chain antikoerper, beta-Tubulin at 56D antikoerper, beta-Tubulin at 60D antikoerper, beta-Tubulin at 85D antikoerper, beta-Tubulin at 97EF antikoerper, beta-tubulin antikoerper, tubulin beta 6 class V antikoerper, beta tubulin antikoerper, tubulin beta class I L homeolog antikoerper, tubulin, beta 5 class I antikoerper, TUBB antikoerper, czcC antikoerper, tbb-6 antikoerper, tubb antikoerper, LOC462399 antikoerper, betaTub56D antikoerper, betaTub60D antikoerper, betaTub85D antikoerper, betaTub97EF antikoerper, Tub1 antikoerper, Tub3 antikoerper, Tub2 antikoerper, Tub4 antikoerper, TVAG_525430 antikoerper, TVAG_062880 antikoerper, TVAG_456920 antikoerper, LOC100101153 antikoerper, TUBB6 antikoerper, Tb927.1.2330 antikoerper, Tb927.1.2350 antikoerper, Tb927.1.2370 antikoerper, Tb927.1.2390 antikoerper, tubb.L antikoerper, Tubb antikoerper, LOC693049 antikoerper, LOC443015 antikoerper, Tubb5 antikoerper

Hintergrund: The microtubules are intracellular dynamic polymers made up of evolutionarily conserved polymorphic alpha/beta-tubulin heterodimers and a large number of microtubule-associated proteins (MAPs). The microtubules consist of 13 protofilaments and have an outer diameter 25 nm. Microtubules have their intrinsic polarity, highly dynamic plus ends and less dynamic minus ends. Microtubules are required for vital processes in eukaryotic cells including mitosis, meiosis, maintenance of cell shape and intracellular transport. Microtubules are also necessary for movement of cells by means of flagella and cilia. In mammalian tissue culture cells microtubules have their minus ends anchored in microtubule organizing centers (MTOCs).The GTP (guanosintriphosphate) molecule is an essential for tubulin heterodimer to associate with other heterodimers to form microtubule. In vivo, microtubule dynamics vary considerably. Microtubule polymerization is reversible and a populations of microtubules in cells are on their minus ends either growing or shortening this phenomenon is called dynamic instability of microtubules. On a practical level, microtubules can easily be stabilized by the addition of non-hydrolysable analogues of GTP (eg. GMPPCP) or more commonly by anti-cancer drugs such as Taxol. Taxol stabilizes microtubules at room temperature for many hours. Using limited proteolysis by enzymes both tubulin subunits can be divided into N-terminal and C-terminal structural domains. The beta-tubulin (relative molecular weight about 50 kDa) is counterpart of alpha-tubulin in tubulin heterodimer, it is coded by multiple tubulin genes and it is also posttranslationally modified. Heterogeneity of subunit is concentrated in C-terminal structural domain.Synonyms: Tubulin beta chain, Tubulin beta-5 chain

Gen-ID: 203068

NCBI Accession: NP_821133

UniProt: P07437

Pathways: Microtubule Dynamics, M Phase