CIAO1 Antikörper (C-Term)

Produktnummer ABIN1109505

Dieses Anti-CIAO1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CIAO1 in WB. Geeignet für Human, Maus, Ratte, Rind (Kuh) und Hund.

Kurzübersicht für CIAO1 Antikörper (C-Term) (ABIN1109505)

Target: CIAO1 (Cytosolic Iron-Sulfur Protein Assembly 1 (CIAO1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CIAO1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CIAO1 Antikörper

Bindungsspezifität: C-Term

Sequenz: LSGFHSRTIY DIAWCQLTGA LATACGDDAI RVFQEDPNSD PQQPTFSLTA

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat, Dog, BovineSpecies reactivity (tested):Human

Aufreinigung: Purified using Protein A affinity column

Immunogen: The immunogen for anti-WDR39 antibody: synthetic peptide directed towards the C terminal of human WDR39

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Add 100 μL of distilled water to a final concentration of 1 mg/mL.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Details zu CIAO1

Target: CIAO1 (Cytosolic Iron-Sulfur Protein Assembly 1 (CIAO1))

Andere Bezeichnung: WDR39 / CIAO1

Hintergrund: WDR39 is a member of the WD40 family of proteins. WDR39 specifically interacts with WT1 both in vitro and in vivo. This interaction results in a decrease in transcriptional activation mediated by WT1. WDR39 does not inhibit binding of WT1 to its consensus nucleotide sequence and does not affect the repression activity of WT1. Thus, WDR39 appears to specifically modulate the transactivation activity of WT1 and may function to regulate the physiological functions of WT1 in cell growth and differentiation.Synonyms: WD repeat-containing protein 39

Gen-ID: 9391

NCBI Accession: NP_004795