Vinculin Antikörper

Produktnummer ABIN1109492

Produktdetails anti-Vinculin Antikörper

Target: Vinculin (VCL)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Vinculin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Spezifität: The antibody reacts with the Vinculin antigen. In Immunoblotting the antibody identifies a 130 kDa polypeptide.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Purified

Immunogen: Purified Vinculin from Human smooth muscle. Hybridoma produced by fusion between myeloma cells and Balb/c spleen cells.

Klon: FB11

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.1 mg/mL

Buffer: PBS, 0.09 % Sodium Azdie, 1 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu Vinculin

Target: Vinculin (VCL)

Abstract: VCL Produkte

Synonyme: CMD1W antikoerper, CMH15 antikoerper, MV antikoerper, MVCL antikoerper, VCL antikoerper, im:6902790 antikoerper, hm:zehn2160 antikoerper, DDBDRAFT_0186762 antikoerper, DDBDRAFT_0232320 antikoerper, DDB_0186762 antikoerper, DDB_0232320 antikoerper, 9430097D22 antikoerper, AA571387 antikoerper, AI462105 antikoerper, AW545629 antikoerper, CG3299 antikoerper, CT11081 antikoerper, Dmel\\CG3299 antikoerper, Dmvincp antikoerper, EG:103B4.1 antikoerper, Vin antikoerper, Vin2EF antikoerper, vinc antikoerper, LOC100228062 antikoerper, vcl-A antikoerper, vinculin antikoerper, vinculin a antikoerper, vinculin A antikoerper, Vinculin antikoerper, vinculin S homeolog antikoerper, VCL antikoerper, vcla antikoerper, vinA antikoerper, Vcl antikoerper, Vinc antikoerper, CpipJ_CPIJ013873 antikoerper, Bm1_37935 antikoerper, vcl antikoerper, vcl.S antikoerper

Hintergrund: Vinculin is an attachment protein involved in the indirect binding of intracellular actin filaments to extracellular fibronectin. Vinculin binds to actin capping protein and alpha actinin, which in turn binds to actin. The binding of fibronectin is also indirect where vinculin binds to talin, which in turn binds to the intracellular domain of the fibronectin receptor which itself is the ligand for fibronectin. Vinculin is widely distributed in tissue and is expressed where smooth muscle actin and fibroblasts attach to the extracellular matrix.Synonyms: Metavinculin

Gen-ID: 7414

NCBI Accession: NP_003364

UniProt: P18206

Pathways: Cell-Cell Junction Organization, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2