TUBB3 Antikörper

Produktnummer ABIN1109374

Dieses Maus Monoklonal-Antikörper erkennt spezifisch TUBB3 in WB, IP, IHC (fro) und EIA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für TUBB3 Antikörper (ABIN1109374)

Target: TUBB3 (Tubulin, beta 3 (TUBB3))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TUBB3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Klon: 3D9

Produktdetails anti-TUBB3 Antikörper

Spezifität: Reacts with Human 55 kDa TUBB3 protein. Cross reacts with Mouse, Rat and other species.

Aufreinigung: Affinity Chromatography on Protein A

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore in distilled water

Konzentration: 1 mg/mL

Buffer: PBS, None

Details zu TUBB3

Target: TUBB3 (Tubulin, beta 3 (TUBB3))

Andere Bezeichnung: TUBB3 / TUBB4

Hintergrund: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non exchangeable site on the alpha-chain. Tubulin is a highly conserved protein with a molecular weight of ~50 kD. Microtubules play key roles in chromosome segregation in mitosis, intracellular transport, ciliary and flagellar bending, and structural support of the cytoskeleton. The two main tubulin isoforms, α- and β-tubulin, are usually products of separate genes. The β-tubulin family includes six expressed genes that produce the polypeptide isoforms known as Classes I through VI, each of which have a distinct pattern of expression. Class III β-tubulin is found in neurons and mammalian testis cells and is widely used as a neuronal marker in developmental neurobiology, neoplasia, and stem cell research. Class III β-tubulin expression in neuronal and neuroblastic tumors is differentiation dependent, and its expression in certain non-neuronal neoplasms has been associated with poor prognosis and/or resistance to chemotherapy.Synonyms: Tubulin beta-3 chain, Tubulin beta-4, Tubulin beta-III

Gen-ID: 10381

Pathways: Microtubule Dynamics, M Phase