TIMD4 Antikörper

Produktnummer ABIN1109254

Dieser Hamster Monoklonal Antikörper detektiert spezifisch TIMD4 in IF, EIA und Func. Es zeigt Reaktivität gegenüber Proben von Maus.

Kurzübersicht für TIMD4 Antikörper (ABIN1109254)

Target: TIMD4 (T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4))

Reaktivität: Maus

Wirt: Hamster

Klonalität: Monoklonal

Konjugat: Dieser TIMD4 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF), Enzyme Immunoassay (EIA), Functional Studies (Func)

Klon: Kat5-18

Produktdetails anti-TIMD4 Antikörper

Spezifität: The monoclonal antibody Kat5-18 recognizes T-cell immunoglobulin and mucin domain containing molecule (TIMD-4, also called TIM-4).

Kreuzreaktivität (Details): Species reactivity (tested):Mouse

Aufreinigung: Purified

Immunogen: Mouse peritoneal cells

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.1 mg/mL

Buffer: PBS, 0.1 % bovine serum albumin

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2 - 8 °C.

Details zu TIMD4

Target: TIMD4 (T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4))

Andere Bezeichnung: TIMD4

Hintergrund: TIMD-4 is a type I transmembrane protein belonging to the immunoglobulin superfamily, containing one Ig-like V-type (immunoglobulin-like) domain. TIMD-4 is expressed in Mac1+ cells in spleen, lymph nodes and fetal liver. TIMD-4 binds apoptotic cells by recognizing phosphatidylserine via its immunoglobulin domain. TIMD-4 in fibroblasts enhanced their ability to engulf apoptotic cells. TIMD-4 is involved in regulating T-cell proliferation and lymphotoxin signaling. TIMD-4 and TIMD-1 are phosphatidylserine receptors for the engulfment of apoptotic cells, and are also involved in intracellular signaling in which exosomes are involved.Synonyms: T-cell immunoglobulin and mucin domain-containing protein 4, T-cell membrane protein 4, TIM-4, TIM4, TIMD-4

Gen-ID: 276891

NCBI Accession: NP_848874

UniProt: Q6U7R4

Pathways: Cancer Immune Checkpoints