TCF7L1 Antikörper (N-Term)
Kurzübersicht für TCF7L1 Antikörper (N-Term) (ABIN1109209)
Target
Alle TCF7L1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- NDELIPFQDE GGEEQEPSSD SASAQRDLDE VKSSLVNESE NQSSSSDSEA
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Kreuzreaktivität (Details)
- Species reactivity (expected):Mouse, Guinea Pig, RabbitSpecies reactivity (tested):Human
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Aufreinigung
- Purified on peptide immunoaffinity column
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Immunogen
- Synthetic peptide directed towards the N terminal of human TCF7L1
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Rekonstitution
- Add 50 μL of distilled water
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store the lyophised antibody at -20 °C for up to one year. Store reconstitued antibody undiluted for one month or in aliquots at -20 °C long term.
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Haltbarkeit
- 12 months
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- TCF7L1 (Transcription Factor 7-Like 1 (T-Cell Specific, HMG-Box) (TCF7L1))
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Andere Bezeichnung
- TCF7L1
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Hintergrund
- TCF7L1 participates in the Wnt signaling pathway. It binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. It is necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis. TCF7L1 down-regulates NQO1, leading to increased mitomycin c resistance.Synonyms: HMG box transcription factor 3, TCF-3, TCF3, Transcription factor 7-like 1
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Gen-ID
- 83439
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NCBI Accession
- NP_112573
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Pathways
- WNT Signalweg, Stem Cell Maintenance
Target
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