TCF7L1 Antikörper (N-Term)

Produktnummer ABIN1109209

Produktdetails anti-TCF7L1 Antikörper

Target: TCF7L1 (Transcription Factor 7-Like 1 (T-Cell Specific, HMG-Box) (TCF7L1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TCF7L1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Sequenz: NDELIPFQDE GGEEQEPSSD SASAQRDLDE VKSSLVNESE NQSSSSDSEA

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Guinea Pig, RabbitSpecies reactivity (tested):Human

Aufreinigung: Purified on peptide immunoaffinity column

Immunogen: Synthetic peptide directed towards the N terminal of human TCF7L1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Add 50 μL of distilled water

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the lyophised antibody at -20 °C for up to one year. Store reconstitued antibody undiluted for one month or in aliquots at -20 °C long term.

Haltbarkeit: 12 months

Details zu TCF7L1

Target: TCF7L1 (Transcription Factor 7-Like 1 (T-Cell Specific, HMG-Box) (TCF7L1))

Andere Bezeichnung: TCF7L1 (TCF7L1 Produkte)

Synonyme: TCF-3 antikoerper, TCF3 antikoerper, Tcf-3 antikoerper, Tcf3 antikoerper, bHLHb21 antikoerper, tcf3c antikoerper, tcf3d antikoerper, xtcf3 antikoerper, XTCF-3 antikoerper, tcf7l1 antikoerper, tcf3b antikoerper, TCF-3-A antikoerper, tcf-3 antikoerper, tcf3 antikoerper, tcf3a antikoerper, zTcf-3 antikoerper, transcription factor 7 like 1 antikoerper, transcription factor 7 like 1 (T cell specific, HMG box) antikoerper, transcription factor 7 like 1 L homeolog antikoerper, transcription factor 7 like 1 S homeolog antikoerper, transcription factor 7 like 1b antikoerper, transcription factor 7 like 1a antikoerper, TCF7L1 antikoerper, Tcf7l1 antikoerper, tcf7l1.L antikoerper, tcf7l1.S antikoerper, tcf7l1b antikoerper, tcf7l1a antikoerper

Hintergrund: TCF7L1 participates in the Wnt signaling pathway. It binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. It is necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis. TCF7L1 down-regulates NQO1, leading to increased mitomycin c resistance.Synonyms: HMG box transcription factor 3, TCF-3, TCF3, Transcription factor 7-like 1

Gen-ID: 83439

NCBI Accession: NP_112573

Pathways: WNT Signalweg, Stem Cell Maintenance