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TCF7L1 Antikörper (N-Term)

TCF7L1 Reaktivität: Human, Maus, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1109209
  • Target Alle TCF7L1 Antikörper anzeigen
    TCF7L1 (Transcription Factor 7-Like 1 (T-Cell Specific, HMG-Box) (TCF7L1))
    Bindungsspezifität
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 35
    • 17
    • 6
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 33
    • 1
    • 1
    Kaninchen
    Klonalität
    • 35
    Polyklonal
    Konjugat
    • 19
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Dieser TCF7L1 Antikörper ist unkonjugiert
    Applikation
    • 19
    • 10
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Sequenz
    NDELIPFQDE GGEEQEPSSD SASAQRDLDE VKSSLVNESE NQSSSSDSEA
    Kreuzreaktivität (Details)
    Species reactivity (expected):Mouse, Guinea Pig, RabbitSpecies reactivity (tested):Human
    Aufreinigung
    Purified on peptide immunoaffinity column
    Immunogen
    Synthetic peptide directed towards the N terminal of human TCF7L1
    Top Product
    Discover our top product TCF7L1 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Rekonstitution
    Add 50 μL of distilled water
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store the lyophised antibody at -20 °C for up to one year. Store reconstitued antibody undiluted for one month or in aliquots at -20 °C long term.
    Haltbarkeit
    12 months
  • Target
    TCF7L1 (Transcription Factor 7-Like 1 (T-Cell Specific, HMG-Box) (TCF7L1))
    Andere Bezeichnung
    TCF7L1 (TCF7L1 Produkte)
    Hintergrund
    TCF7L1 participates in the Wnt signaling pathway. It binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. It is necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis. TCF7L1 down-regulates NQO1, leading to increased mitomycin c resistance.Synonyms: HMG box transcription factor 3, TCF-3, TCF3, Transcription factor 7-like 1
    Gen-ID
    83439
    NCBI Accession
    NP_112573
    Pathways
    WNT Signalweg, Stem Cell Maintenance
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