SPTA1 Antikörper

Produktnummer ABIN1109120

Produktdetails anti-SPTA1 Antikörper

Target: SPTA1 (Spectrin alpha 1, Erythrocytic (SPTA1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SPTA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Spezifität: The antibody clone AF10 is specific to the 240 kDa Erythroid alpha-Spectrin. This antibody is suitable for Various immunochemical reactions to detect Erythroid Spectrins, Identification of Erythroid leukemias (Ref.1).

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Purified

Immunogen: Ghost proteins of Human red blood cells. Hybridoma produced by fusion between myeloma cells and Balb/c spleen cells.

Klon: AF10

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.1 mg/mL

Buffer: PBS, 0.09 % Sodium Azide, 1.0 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu SPTA1

Target: SPTA1 (Spectrin alpha 1, Erythrocytic (SPTA1))

Andere Bezeichnung: Spectrin alpha Chain (Erythrocyte) / SPTA1 (SPTA1 Produkte)

Synonyme: Spna1 antikoerper, AF093576 antikoerper, AI451697 antikoerper, Spna-1 antikoerper, ha antikoerper, ihj antikoerper, nmf4 antikoerper, sph antikoerper, EL2 antikoerper, HPP antikoerper, HS3 antikoerper, SPH3 antikoerper, SPTA antikoerper, spectrin, alpha, erythrocytic 1 antikoerper, spectrin alpha, erythrocytic 1 antikoerper, Spta1 antikoerper, SPTA1 antikoerper

Hintergrund: Erythroid spectrins, some other proteins of erythroid cytoskeleton, and the transmembrane protein band 3 are highly specific for erythrocytes and their progenitors. They are more reliable markers for erythroid differentiation than Glycophorin A, the commonly used marker for erythroid differentiation, because Glycophorin A is expressed also in many cell lines otherwise exhibiting mainly megakaryotic charasteristics.Synonyms: Erythroid alpha-spectrin, SPTA

Gen-ID: 6708

NCBI Accession: NP_003117

UniProt: P02549

Pathways: Regulation of Actin Filament Polymerization