PRTN3 Antikörper
Kurzübersicht für PRTN3 Antikörper (ABIN1108718)
Target
Alle PRTN3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- This antibody reacts to Proteinase 3.
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Kreuzreaktivität (Details)
- Species reactivity (tested):Human.
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Aufreinigung
- Affinity chromatography on Protein G
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Isotyp
- IgG2b
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- PBS, 0.03 % sodium azide, 50 % glycerol
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- PRTN3 (Proteinase 3 (PRTN3))
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Andere Bezeichnung
- PR3 / C-ANCA
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Hintergrund
- Proteinase 3, also known as PRTN3. PRTN3 is a serine protease enzyme expressed mainly in neutrophil granulocytes. Its exact role in the function of the neutrophil is unknown but in human neutrophils proteinase 3 contributes to the proteolytic generation of antimicrobial peptides. It is also the epitope of anti-neutrophil cytoplasmic antibodies (ANCAs) of the cANCA (cytoplasmic subtype) class, a type of antibody frequently found in the disease Wegener's granulomatosis.Synonyms: AGP7, Leukocyte proteinase 3, MBN, Myeloblastin, NP-4, Neutrophil proteinase 4, P29, PR-3, PRTN3, Proteinase 3, Wegener autoantigen
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Molekulargewicht
- 28 kDa
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Gen-ID
- 5657
Target
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