Polymyxin B Antikörper

Produktnummer ABIN1108692

Der Maus Monoklonal anti-Polymyxin B Antikörper (Klon 45) (ABIN1108692) detektiert spezifisch Polymyxin B in WB und EIA. Dieser Antikörper reagiert spezifisch mit Proben aus Bacillus polymyxa.

Kurzübersicht für Polymyxin B Antikörper (ABIN1108692)

Target: Polymyxin B

Reaktivität: Bacillus polymyxa

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Polymyxin B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Klon: 45

Produktdetails anti-Polymyxin B Antikörper

Endotoxin-Niveau: Low Endotoxin

Isotyp: IgM

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: > 0.2 mg/mL

Buffer: 0.02 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Polymyxin B

Target: Polymyxin B

Hintergrund: The peptide antibiotic Polymyxin B (PMB) binds to bacterial endotoxin (lipopolysaccharide, LPS). The interaction of PMB with LPS involves ionic forces between amino groups in PMB and negatively charged phosphate and carboxyl groups in the lipid A-Kdo region. PMB has relevance for endotoxin research in at least two ways: first, PMB reacts with LPS of many species regardless of varied serospecificity, and thus it can be used as a general probe for measuring or detecting LPS or lipid A. Second, binding of PMB to LPS may result in neutralization of the detrimental effects of LPS either in vitro or in vivo.