PLVAP Antikörper (FITC)

Produktnummer ABIN1108673

Der Maus Monoklonal Anti-PLVAP-Antikörper wurde für WB, IHC (fro) und IF validiert. Er ist geeignet, PLVAP in Proben von Human zu detektieren.

Kurzübersicht für PLVAP Antikörper (FITC) (ABIN1108673)

Target: PLVAP (Plasmalemma Vesicle Associated Protein (PLVAP))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PLVAP Antikörper ist konjugiert mit FITC

Applikation: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF)

Klon: 174-2

Produktdetails anti-PLVAP Antikörper (FITC)

Kreuzreaktivität (Details): Species reactivity (tested):Human

Aufreinigung: Protein G

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.1 mg/mL

Buffer: PBS, 0.02 % sodium azide, 1 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2 - 8 °C.

Details zu PLVAP

Target: PLVAP (Plasmalemma Vesicle Associated Protein (PLVAP))

Andere Bezeichnung: PLVAP

Hintergrund: PLVAP is a 60 kDa type II transmembrane glycoprotein which tends to form homodimers. PLVAP is widely expressed in the vasculature of normal tissues. The vascular staining pattern of PLVAP is quite unique among the endothelial cell antigens, since expression of other antigens (like ICAM-1, P-selectin, E-selectin or VCAM-1) is not limited to vascular endothelial cells. PLVAP expression in the vascular endothelial cells of the CNS is lost in association with formation of an intact blood-brain barrier. However, in the endothelium of human brain tumors expression of PLVAP is specifically up-regulated, making it a suitable antiangiogenic target for brain tumor therapy and cerebral edema. Furthermore, PLVAP is expressed in the vasculature of most other human tumors and as such useful as marker for tumor angiogenesis.Synonyms: Endothelial Cell Antigen, Endothelial cell marker, Endothelial cell surface marker, FELS, Fenestrated endothelial-linked structure protein, MECA-32 antigen, PV-1, PV1, Plasmalemma vesicle protein 1, Plasmalemma vesicle-associated protein

UniProt: Q9BX97