PNPLA6 Antikörper (C-Term)

Produktnummer ABIN1108496

Der Kaninchen Polyklonal Anti-PNPLA6-Antikörper wurde für WB, IHC (p) und IHC (fro) validiert. Er ist geeignet, PNPLA6 in Proben von Zebrafisch (Danio rerio) zu detektieren.

Kurzübersicht für PNPLA6 Antikörper (C-Term) (ABIN1108496)

Target: PNPLA6 (Patatin-Like phospholipase Domain Containing 6 (PNPLA6))

Reaktivität: Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PNPLA6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-PNPLA6 Antikörper

Bindungsspezifität: AA 1323-1348, C-Term

Spezifität: This antibody detects NTE at aa 1323-1348. No cross reactivity with other proteins.

Kreuzreaktivität (Details): Species reactivity (tested):Zebrafish

Aufreinigung: Immunogen affinity purified

Immunogen: Synthetic peptide corresponding to a sequence at the C-terminal of fish PNPLA6 (1323-1348 amino acid)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3

Konservierungsmittel: Sodium azide, Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu PNPLA6

Target: PNPLA6 (Patatin-Like phospholipase Domain Containing 6 (PNPLA6))

Andere Bezeichnung: NTE

Hintergrund: Patatin-like phospholipase domain containing 6 (PNPLA6), also known as Neuropathy target esterase (NTE), is a human gene. Neuropathy target esterase (NTE) is involved in neural development and is the target for neurodegeneration induced by selected organophosphorus pesticides and chemical warfare agents. The genetic or chemical reduction of Nte activity results in a neurological phenotype of hyperactivity in mammals and indicate that EOPF toxicity occurs directly through inhibition of Nte without the requirement for Nte gain of function or aging.Synonyms: Neuropathy target esterase, PNPLA6

Gen-ID: 10908

NCBI Accession: NP_006693

UniProt: Q8IY17

Pathways: Ribonucleoside Biosynthetic Process