PRG2 Antikörper

Produktnummer ABIN110842

Dieses Maus Monoklonal-Antikörper erkennt spezifisch PRG2 in WB, IHC (p), IHC (fro) und EIA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für PRG2 Antikörper (ABIN110842)

Target: PRG2 (Bone Marrow Proteoglycan (PRG2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PRG2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Klon: BMK13

Produktdetails anti-PRG2 Antikörper

Spezifität: Specific for eosinophil major basic protein irrespective of the stages of eosinophil activation and can be regarded as an eosinophil marker. The antibody will recognize the 23.8 kDa secreted pro-form of MBP (Pregnancy associated MBP) and the 13.8 kDa mature form found in the matrix of the eosinophil large specific granule. Does not cross-react with horse, mouse or rat MBP.

Aufreinigung: Protein A chromatography

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: IHC with fresh frozen tissue (fix in methanol: acetone)IHC with formalin fixed paraffin-embedded tissue (treat with 0.1 % trypsin before blocking)Western blotELISA
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.1 mg/mL

Buffer: PBS with 0.09 % sodium azide as preservative and 0.1 % BSA as stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.

Details zu PRG2

Target: PRG2 (Bone Marrow Proteoglycan (PRG2))

Andere Bezeichnung: Proteoglycan 2

Hintergrund: PRG2 is a cytotoxin and helminthotoxin. It also induces noncytolytic histamine release from human basophils and is involved in antiparasitic defense mechanisms and immune hypersensitivity reactions. The proform acts as a proteinase inhibitor, reducing the activity of PAPPA. In pregnancy serum, the proform exists as a disulfide-linked 2:2 heterotetramer with PAPPA, as a disulfide-linked 2:2 heterotetramer with AGT, and as a complex (probably a 2:2:2 heterohexamer) with AGT and C3dg.Synonyms: BMPG, Bone marrow proteoglycan, EMBP, Eosinophil granule major basic protein, PRG2, Pregnancy-associated major basic protein

Gen-ID: 5553

NCBI Accession: NP_002719

UniProt: P13727