PRG2 Antikörper (AA 17-222)
Kurzübersicht für PRG2 Antikörper (AA 17-222) (ABIN3016204)
Target
Alle PRG2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 17-222
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Sequenz
- LHLRSETSTF ETPLGAKTLP EDEETPEQEM EETPCRELEE EEEWGSGSED ASKKDGAVES ISVPDMVDKN LTCPEEEDTV KVVGIPGCQT CRYLLVRSLQ TFSQAWFTCR RCYRGNLVSI HNFNINYRIQ CSVSALNQGQ VWIGGRITGS GRCRRFQWVD GSRWNFAYWA AHQPWSRGGH CVALCTRGGH WRRAHCLRRL PFICSY
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 17-222 of human PRG2 (NP_002719.3).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- PRG2 (Bone Marrow Proteoglycan (PRG2))
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Andere Bezeichnung
- PRG2
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Hintergrund
- The protein encoded by this gene is the predominant constituent of the crystalline core of the eosinophil granule. High levels of the proform of this protein are also present in placenta and pregnancy serum, where it exists as a complex with several other proteins including pregnancy-associated plasma protein A (PAPPA), angiotensinogen (AGT), and C3dg. This protein may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin, and in immune hypersensitivity reactions. The encoded protein contains a peptide that displays potent antimicrobial activity against Gram-positive bacteria, Gram-negative bacteria, and fungi. It is directly implicated in epithelial cell damage, exfoliation, and bronchospasm in allergic diseases. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,PRG2,BMPG,MBP,MBP1,proMBP,PRG2
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Molekulargewicht
- 23 kDa/25 kDa
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Gen-ID
- 5553
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UniProt
- P13727
Target
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