Myeloperoxidase Antikörper (C-Term)

Produktnummer ABIN1108338

Dieses Anti-Myeloperoxidase-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Myeloperoxidase in WB, IF und IHC (p). Geeignet für Human, Maus und Ratte. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für Myeloperoxidase Antikörper (C-Term) (ABIN1108338)

Target: Myeloperoxidase (MPO)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Myeloperoxidase Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Myeloperoxidase Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody detects Myeloperoxidase at C-term. No cross reactivity with other proteins.

Kreuzreaktivität (Details): Species reactivity (tested):Human, Mouse, Rat.

Aufreinigung: Immunogen Affinity Chromatography

Immunogen: Synthetic peptide corresponding to a sequence mapping at the C-terminal of human MPO .Remarks: Sequence is identical to the related mouse and rat sequence

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium Azide

Konservierungsmittel: Sodium azide, Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Referenzen für anti-Myeloperoxidase Antikörper (ABIN1108338)

Chang, Tseng, Lee, Hwang, Chen, Su, Chong, Lan, Wu, Chen, Lu, Liao, Hsueh, Hsieh: "β-Nitrostyrene derivatives attenuate LPS-mediated acute lung injury via the inhibition of neutrophil-platelet interactions and NET release." in: American journal of physiology. Lung cellular and molecular physiology, (2017) (PubMed).

Details zu Myeloperoxidase

Target: Myeloperoxidase (MPO)

Andere Bezeichnung: Myeloperoxidase

Hintergrund: Myeloperoxidase (MPO) is a mammalian phagocyte hemoprotein thought to primarily mediate host defense reactions. It is abundantly expressed in neutrophils and secreted during their activation. Myeloperoxidase is part of the host defense system of human polymorphonuclear leukocytes, responsible for microbicidal activity against a wide range of organisms. It is located in the nucleus as well as in the cytoplasm. Intranuclear MPO may help to protect DNA against damage resulting from oxygen radicals produced during myeloid cell maturation and function.Synonyms: MPO

Gen-ID: 4353

NCBI Accession: NP_000241

UniProt: P05164

Pathways: Chromatin Binding