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Myeloperoxidase Antikörper (C-Term)

Name: Myeloperoxidase Antikörper (C-Term)
SKU: ABIN1108338
Price: 842.77 EUR
Availability: InStock

MPO Reaktivität: Human, Maus, Ratte WB, IF, IHC (p) Wirt: Kaninchen Polyclonal unconjugated

Western blot analysis of rat brain tissue lysis using Myeloperoxidase antibody (Myeloperoxidase Antikörper (C-Term))

Immunohistochemical analysis of paraffin embedded Human tissue sections (ovary) using Myeloperoxidase antibody (Myeloperoxidase Antikörper (C-Term))

IHC (p)

2 Abbildungen

(1 reference)

Produktnummer ABIN1108338

Datenblatt (PDF)

Target Alle Myeloperoxidase (MPO) Antikörper anzeigen

Myeloperoxidase (MPO)
Bindungsspezifität
16

12

12

10

10

9

8

4

3

3

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
C-Term
Reaktivität
171

60

53

5

2

1

1

1

1

1
Human, Maus, Ratte
Wirt
126

81

1

1

1
Kaninchen
Passende Sekundärantikörper
Klonalität
118

92
Polyklonal
Konjugat
95

29

27

10

9

9

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser Myeloperoxidase Antikörper ist unkonjugiert
Applikation
116

86

61

59

30

28

28

20

17

14

14

13

10

7

7

5

5

2

2

1

1

1

1

1

1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität

This antibody detects Myeloperoxidase at C-term. No cross reactivity with other proteins.

Kreuzreaktivität (Details)

Species reactivity (tested):Human, Mouse, Rat.

Aufreinigung

Immunogen Affinity Chromatography

Immunogen

Synthetic peptide corresponding to a sequence mapping at the C-terminal of human MPO .Remarks: Sequence is identical to the related mouse and rat sequence

Isotyp

IgG

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Applikationshinweise

Optimal working dilution should be determined by the investigator.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Rekonstitution

0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer

5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium Azide

Konservierungsmittel

Sodium azide, Thimerosal (Merthiolate)

Vorsichtsmaßnahmen

This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung

Avoid repeated freezing and thawing.

Lagerung

4 °C/-20 °C

Informationen zur Lagerung

Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Chang, Tseng, Lee, Hwang, Chen, Su, Chong, Lan, Wu, Chen, Lu, Liao, Hsueh, Hsieh: "β-Nitrostyrene derivatives attenuate LPS-mediated acute lung injury via the inhibition of neutrophil-platelet interactions and NET release." in: American journal of physiology. Lung cellular and molecular physiology, (2017) (PubMed).
Target

Myeloperoxidase (MPO)

Andere Bezeichnung

Myeloperoxidase (MPO Produkte)

Hintergrund

Myeloperoxidase (MPO) is a mammalian phagocyte hemoprotein thought to primarily mediate host defense reactions. It is abundantly expressed in neutrophils and secreted during their activation. Myeloperoxidase is part of the host defense system of human polymorphonuclear leukocytes, responsible for microbicidal activity against a wide range of organisms. It is located in the nucleus as well as in the cytoplasm. Intranuclear MPO may help to protect DNA against damage resulting from oxygen radicals produced during myeloid cell maturation and function.Synonyms: MPO

Gen-ID

4353

NCBI Accession

NP_000241

UniProt

P05164

Pathways

Chromatin Binding