MRGBP Antikörper (N-Term)

Produktnummer ABIN1108299

Produktdetails anti-MRGBP Antikörper

Target: MRGBP (MRG-Binding Protein (MRGBP))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MRGBP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MGEAEVGGGG AAGDKGPGEA ATSPAEETVV WSPEVEVCLF HAMLGHKPVG

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, BovineSpecies reactivity (tested):Human

Aufreinigung: Purified using Protein A affinity column

Immunogen: The immunogen for anti-C20ORF20 antibody: synthetic peptide directed towards the N terminal of human C20ORF20

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Add 100 μL of distilled water to a final concentration of 1 mg/mL.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Details zu MRGBP

Target: MRGBP (MRG-Binding Protein (MRGBP))

Andere Bezeichnung: MRGBP (MRGBP Produkte)

Hintergrund: MRGBP alos called C20orf20 is a component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage.Synonyms: C20orf20, MRG-binding protein

Gen-ID: 55257

NCBI Accession: NP_060740