CCL2 Antikörper

Produktnummer ABIN1108184

Der Maus Monoklonal Anti-CCL2-Antikörper wurde für WB, IP, IHC (p), Neut, EIA und IHC (fro) validiert. Er ist geeignet, CCL2 in Proben von Maus zu detektieren.

Kurzübersicht für CCL2 Antikörper (ABIN1108184)

Target: CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))

Reaktivität: Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CCL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Neutralization (Neut), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: MNA1

Produktdetails anti-CCL2 Antikörper

Kreuzreaktivität (Details): Species reactivity (tested):Mouse.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0,1 mg/mL

Buffer: PBS, 0,1 % BSA

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu CCL2

Target: CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))

Andere Bezeichnung: MCP1 / CCL2

Hintergrund: Monocyte chemotactic protein-1 (MCP-1) belong to the b or CC family of chemotactic cytokines, or chemokines, which stimulate the migration of monocytic cells. In contrast, the CXC chemokines predominantly activate polymorphonuclear leukocytes. The coordinated synthesis and release of MCP-1 plays a central role in both acute and chronic inflammatory processes by controlling the influx of phagocytic cells. Furthermore, their state of activation is in concert with primary inflammatory cytokines, such as interleukin-1 (IL-1), tumor necrosis factor-alpha (TNF-a), and IL-6. A selective accumulation of MCP-1 in the cerebrospinal fluid (CSF) of AIDS patients with cytomegalovirus (CMV) encephalitis, but not with other opportunistic infections (OI) or primary lymphomas of the central nervous system (CNS), has been described.Synonyms: C-C motif chemokine 2, HC-11, HC11, MCAF, MCP-1, Monocyte chemoattractant protein 1, Monocyte chemotactic and activating factor, Monocyte chemotactic protein 1, Monocyte secretory protein JE, SCYA2, Small-inducible cytokine A2

Gen-ID: 10090

UniProt: P10148

Pathways: Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, ER-Nucleus Signaling, Unfolded Protein Response, Phosphorylierungen bei SARS-CoV-2 Infektion