M-CSF/CSF1 Antikörper

Produktnummer ABIN1108092

Der Ratte Monoklonal anti-M-CSF/CSF1 Antikörper (Klon ER-MP58) (ABIN1108092) detektiert spezifisch M-CSF/CSF1 in FACS und IHC (fro). Dieser Antikörper reagiert spezifisch mit Proben aus Maus.

Kurzübersicht für M-CSF/CSF1 Antikörper (ABIN1108092)

Target: M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser M-CSF/CSF1 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: ER-MP58

Produktdetails anti-M-CSF/CSF1 Antikörper

Spezifität: The monoclonal antibody ER-MP58 recognizes an antigen present on all mouse macrophage colony-stimulating factor (M-CSF) responsive cells in the bone marrow, including the earliest colony-forming myeloid progenitors, as well as by the majority of other myeloid precursors. The antigen is detected on a broad development range of macrophage precursor cells ut to the monocytic level, but also on grnaulocytes. ERxpression is rapidly lost upon maturation beyond the monocytic stage. The antigen disappears in the course of macrophage differentiation. Furthermore the antigen is clearly different from commenly used myeloid markers as Mac-1, F4/80, and Gr-1. The monoclonal antibody ER-MP58 is very useful for the identification of mouse myeloid hemopoietic islands in various organs, and for embryonal studies. Cells committed to the myeloid lineage can be separated from progenitor cells with other differentiation capacities by means of multiparameter cell sorting using monoclonal antibody ER-MP58 in combination with monoclonal antibody ER-MP12 and ER-MP-20.

Kreuzreaktivität (Details): Species reactivity (tested):Mouse

Aufreinigung: Protein G

Immunogen: Balb/c macrophage precursor cell hybrids

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.1 mg/mL

Buffer: PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Prior to reconstitution store at -70 °C. Following reconstitution store the antibody (in aliquots) at < -20 °C for at least 6 month.

Haltbarkeit: 6 months

Details zu M-CSF/CSF1

Target: M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))

Andere Bezeichnung: Macrophage Colony Stimulating Factor (M-CSF)

Hintergrund: Synonyms: CSF-1, CSF1, MCSF, Macrophage colony-stimulating factor 1

Gen-ID: 12977

NCBI Accession: NP_001107001

UniProt: P07141

Pathways: RTK Signalweg