Lamin B1 Antikörper (C-Term)

Produktnummer ABIN1108013

Produktdetails anti-Lamin B1 Antikörper

Target: Lamin B1 (LMNB1)

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Lamin B1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Spezifität: This antibody detects Lamin Beta at C-term. No cross reactivity with other proteins.

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat

Aufreinigung: Immunogen affinity purified

Immunogen: Synthetic peptide corresponding to a sequence at the C-terminal of human Lamin B .Remarks: Sequence is different from the related rat and mouse sequence by three amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3

Konservierungsmittel: Sodium azide, Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu Lamin B1

Target: Lamin B1 (LMNB1)

Andere Bezeichnung: Lamin-B1 (LMNB1) (LMNB1 Produkte)

Synonyme: MGC52550 antikoerper, Lamin-L(I) antikoerper, lamin-b antikoerper, lmn antikoerper, lmn2 antikoerper, lmnb antikoerper, LMNB1 antikoerper, ADLD antikoerper, LMN antikoerper, LMN2 antikoerper, LMNB antikoerper, fc06g01 antikoerper, wu:fc06g01 antikoerper, lamin B1 L homeolog antikoerper, lamin B1 antikoerper, lmnb1.L antikoerper, lmnb1 antikoerper, LMNB1 antikoerper, Lmnb1 antikoerper

Hintergrund: Lamins are the major components of the nuclear lamina which underlies the nuclear envelope of eukaryotic cells. lamin B is a structural component of the long-sought-after spindle matrix that promotes microtubule assembly and organization in mitosis. Inspection of the deduced amino acid sequence of lamin B revealed the presence in coil 1B of the alpha-helical domain of a leucine heptad repeat region.Lamin B assembled into a matrix-like network in mitosis through a process that depended on the presence of the guanosine triphosphate-bound form of the small guanosine triphosphatase Ran.Synonyms: LMN2, LMNB, Lamin B1, Lamin B1/B2, Lamin B2

Gen-ID: 4001

NCBI Accession: NP_005564

UniProt: P20700

Pathways: Apoptose, Caspase Kaskade in der Apoptose